CVN03650
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MedKoo CAT#: 556159

CAS#: 2446803-65-0

Description: CVN03650, also known as IL-17 modulator 4, is an IL-17 modulator. This compound was first reported in Journal of Medicinal Chemistry (2022), 65(13), 8828-8842 (Compound 23). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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CVN03650
CAS# 2446803-65-0
Instruction

Theoretical Analysis

MedKoo Cat#: 556159
Name: CVN03650
CAS#: 2446803-65-0
Chemical Formula: C27H34N6O2
Exact Mass: 474.27
Molecular Weight: 474.609
Elemental Analysis: C, 68.33; H, 7.22; N, 17.71; O, 6.74

Price and Availability

Size Price Availability Quantity
100mg USD 3850 2 Weeks
200mg USD 6450 2 Weeks
1g USD 12950 2 Weeks
Bulk inquiry

Synonym: IL-17 modulator 4; CVN03650; CVN 03650; CVN 03650;

IUPAC/Chemical Name: 1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-

InChi Key: CQKVACARDGYEMU-VWLOTQADSA-N

InChi Code: InChI=1S/C27H34N6O2/c1-15(2)33-22(13-14-28-33)26(34)30-25(24(19-5-6-19)20-7-8-20)27(35)29-21-11-9-18(10-12-21)23-16(3)31-32-17(23)4/h9-15,19-20,24-25H,5-8H2,1-4H3,(H,29,35)(H,30,34)(H,31,32)/t25-/m0/s1

SMILES Code: O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Journal of Medicinal Chemistry (2022), 65(13), 8828-8842

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 474.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Journal of Medicinal Chemistry (2022), 65(13), 8828-8842