WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 205813
Description: APC-200 has demonstrated the ability to inhibit reactive oxygen species (ROS) formation specifically in prostate cancer cells and thereby blocks inflammation and androgen induced oxidative stress. Whereas acute inflammation is important for host defense, chronic inflammation contributes to tumor growth, progression to castrate resistant tumors and metastatic progression. In animal studies conducted to date, APC-200 was not only an excellent inhibitor of chronic inflammation, but also significantly delayed prostate cancer progression and increased survival in animal disease models. APC-200 is being developed as an orally administered drug and is in late-stage preclinical development.
MedKoo Cat#: 205813
Synonym: APC200; APC-200; APC 200.
IUPAC/Chemical Name: NONE
1: Sato T, Ohkusa T, Suzuki S, Nao T, Yano M, Matsuzaki M. High ambient pressure produces hypertrophy and up-regulates cardiac sarcoplasmic reticulum Ca2+ regulatory proteins in cultured rat cardiomyocytes. Hypertens Res. 2006 Dec;29(12):1013-20. PubMed PMID: 17378374.