WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 200200
CAS#: 150091-68-2 (2HCl)
Description: Amonafide dihydrochloride is the dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.
MedKoo Cat#: 200200
Name: Amonafide dihydrochloride
CAS#: 150091-68-2 (2HCl)
Chemical Formula: C16H19Cl2N3O2
Exact Mass:
Molecular Weight: 283.32508
Elemental Analysis: C, 53.94; H, 5.38; Cl, 19.90; N, 11.80; O, 8.98
Amonafide dihydrochloride, purity > 98%, is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Related CAS #: 69408-81-7 (free base) 150091-68-2 (2HCl) 618863-54-0 (malate) 618863-60-8
Synonym: amonafide; amonafide hydrochloride; benzisoquinolinedione; nafidimide. US brand name: Quinamed. Abbreviations: AMON. BIDA. Code name: MFA142.
IUPAC/Chemical Name: 5-amino-2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione dihydrochloride
InChi Key: AEMLYYQEBPJIEO-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H17N3O2.2ClH/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21;;/h3-5,8-9H,6-7,17H2,1-2H3;2*1H
SMILES Code: O=C1N(CCN(C)C)C(C2=CC(N)=CC3=CC=CC1=C23)=O.[H]Cl.[H]Cl
The following data is based on the product molecular weight 283.32508 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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