Pyrocatechol Violet

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 208515

CAS#: 115-41-3

Description: Pyrocatechol Violet is a dye that can be used as a marker to characterize liposomal membrane permeability using the chelation and the first-order derivative spectrophotometry

Chemical Structure

Pyrocatechol Violet
CAS# 115-41-3

Theoretical Analysis

MedKoo Cat#: 208515
Name: Pyrocatechol Violet
CAS#: 115-41-3
Chemical Formula: C19H14O7S
Exact Mass: 386.046
Molecular Weight: 386.37
Elemental Analysis: C, 59.06; H, 3.65; O, 28.99; S, 8.30

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: EINECS 204-088-3, NSC 622476, NSC 8805, PKF, Pyrocatechinsulfonephthalein

IUPAC/Chemical Name: 1,2-Benzenediol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-


InChi Code: InChI=1S/C19H14O7S/c20-14-7-5-11(9-16(14)22)19(12-6-8-15(21)17(23)10-12)13-3-1-2-4-18(13)27(24,25)26-19/h1-10,20-23H

SMILES Code: O=S1(OC(C2=CC=C(O)C(O)=C2)(C3=CC=C(O)C(O)=C3)C4=CC=CC=C41)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 386.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Yadav P, Zelder F. Detection of glyphosate with a copper(II)-pyrocatechol violet based GlyPKit. Anal Methods. 2021 Oct 8;13(38):4354-4360. doi: 10.1039/d1ay01168e. PMID: 34570143; PMCID: PMC8498994.

2: Ozkantar N, Yilmaz E, Soylak M, Tuzen M. Pyrocatechol violet impregnated magnetic graphene oxide for magnetic solid phase microextraction of copper in water, black tea and diet supplements. Food Chem. 2020 Aug 15;321:126737. doi: 10.1016/j.foodchem.2020.126737. Epub 2020 Apr 2. PMID: 32278275.

3: MACEK K, MORAVEK L. Pyrocatechol violet as a detection reagent for cations. Nature. 1956 Jul 14;178(4524):102-3. doi: 10.1038/178102a0. PMID: 13348643.

4: Ullah N, Erten-Ela Ş, Mujtaba Shah S, Hussain H, Ansir R, Qamar S. Selected organic dyes (carminic acid, pyrocatechol violet and dithizone) sensitized metal (silver, neodymium) doped TiO2/ZnO nanostructured materials: A photoanode for hybrid bulk heterojunction solar cells. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Oct 5;278:121387. doi: 10.1016/j.saa.2022.121387. Epub 2022 May 14. PMID: 35597162.

5: Amin AS. Pyrocatechol violet in pharmaceutical analysis. Part I. A spectrophotometric method for the determination of some beta-lactam antibiotics in pure and in pharmaceutical dosage forms. Farmaco. 2001 Mar;56(3):211-8. doi: 10.1016/s0014-827x(01)01078-3. PMID: 11409329.

6: Jin Y, Li M, Hou X. Pyrocatechol violet as a marker to characterize liposomal membrane permeability using the chelation and the first-order derivative spectrophotometry. J Pharm Biomed Anal. 2005 Feb 23;37(2):379-82. doi: 10.1016/j.jpba.2004.10.019. PMID: 15708681.

7: De Silva DA, Halstead AC, Côté AM, Sabr Y, von Dadelszen P, Magee LA. Unexpected random urinary protein:creatinine ratio results-limitations of the pyrocatechol violet-dye method. BMC Pregnancy Childbirth. 2013 Jul 17;13:152. doi: 10.1186/1471-2393-13-152. PMID: 23865673; PMCID: PMC3733961.

8: Starczewska B, Jasińska A, Białous B. Study and analytical application of ion-pair formation in the system fluoxetine-pyrocatechol violet and fluvoxamine- pyrocatechol violet. Pharmazie. 2003 Apr;58(4):245-8. PMID: 12749405.

9: Shivakiran MS, Venkataramana M, Lakshmana Rao PV. Rapid onsite detection of bacterial spores of biothreat importance by paper-based colorimetric method using erbium-pyrocatechol violet complex. Appl Microbiol Biotechnol. 2016 Jan;100(2):893-901. doi: 10.1007/s00253-015-7151-7. Epub 2015 Nov 25. PMID: 26603759.

10: Su J, Sun YQ, Huo FJ, Yang YT, Yin CX. Naked-eye determination of oxalate anion in aqueous solution with copper ion and pyrocatechol violet. Analyst. 2010 Nov;135(11):2918-23. doi: 10.1039/c0an00620c. Epub 2010 Sep 28. PMID: 20877823.