WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556149
CAS#: 84477-87-2 (free base)
Description: H-7 is a specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
MedKoo Cat#: 556149
Name: H-7 inhibitor
CAS#: 84477-87-2 (free base)
Chemical Formula: C14H17N3O2S
Exact Mass: 291.1041
Molecular Weight: 291.369
Elemental Analysis: C, 57.71; H, 5.88; N, 14.42; O, 10.98; S, 11.00
Related CAS #: 108930-17-2 (HCl) 84477-87-2 (free base)
Synonym: H-7 inhibitor; H-7 free base,
IUPAC/Chemical Name: 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine
InChi Key: BDVFVCGFMNCYPV-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3
SMILES Code: CC1N(S(=O)(C2=CC=CC3=C2C=CN=C3)=O)CCNC1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 291.369 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
