WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 578648
CAS#: 877467-35-1
Description: O-3367 is a biochemical shown to attenuate the BLT receptor-mediated ability of LTB(4) to induce migration in neutrophils.
MedKoo Cat#: 578648
Name: O-3367
CAS#: 877467-35-1
Chemical Formula: C25H44FN3O5S2
Exact Mass: 549.2706
Molecular Weight: 549.76
Elemental Analysis: C, 54.62; H, 8.07; F, 3.46; N, 7.64; O, 14.55; S, 11.66
This product is not in stock, which may be available by custom synthesis.
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Synonym: O-3367; O 3367; O3367
IUPAC/Chemical Name: N-(2-Fluoro-4-(((((11-hydroxy-8-heptadecen-1-yl)amino)sulfonyl)amino)methyl)phenyl)methanesulfonamide
InChi Key: UDFBEDHJBCODPQ-JLHYYAGUSA-N
InChi Code: 1S/C25H44FN3O5S2/c1-3-4-5-12-15-23(30)16-13-10-8-6-7-9-11-14-19-27-36(33,34)28-21-22-17-18-25(24(26)20-22)29-35(2,31)32/h10,13,17-18,20,23,27-30H,3-9,11-12,14-16,19,21H2,1-2H3/b13-10+
SMILES Code: CCCCCCC(O)C\C=C\CCCCCCCNS(=O)(=O)NCc1ccc(NS(=O)(=O)C)c(F)c1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 549.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. McHugh D, McMaster RS, Pertwee RG, Roy S, Mahadevan A, Razdan RK, Ross RA. Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors. J Pharmacol Exp Ther. 2006 Feb;316(2):955-65. doi: 10.1124/jpet.105.095992. Epub 2005 Oct 5. PMID: 16207832.
