Formylmelphalan
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 100382

CAS#: 7789-59-5

Description: Formylmelphalan was approved in China for treating cancer. Formylmelphalan is an alkylating agents, which could cross-link DNA.


Chemical Structure

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Formylmelphalan
CAS# 7789-59-5

Theoretical Analysis

MedKoo Cat#: 100382
Name: Formylmelphalan
CAS#: 7789-59-5
Chemical Formula: C14H18Cl2N2O3
Exact Mass: 332.06945
Molecular Weight: 333.21
Elemental Analysis: C, 50.46; H, 5.44; Cl, 21.28; N, 8.41; O, 14.40

Price and Availability

Size Price Availability Quantity
25.0g USD 265.0 2 Weeks
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Synonym: NFormylmelphalan; NFormylLsarcolysin; NFormylLpsarcolysin; CB 3208; NSC 37024; NSC37024; LS15879.

IUPAC/Chemical Name: 3-[4-[bis(2-chloroethyl)amino]phenyl]-2-formamidopropanoic acid

InChi Key: ZPOLNCDBPYJDSE-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H18Cl2N2O3/c15-5-7-18(8-6-16)12-3-1-11(2-4-12)9-13(14(20)21)17-10-19/h1-4,10,13H,5-9H2,(H,17,19)(H,20,21)

SMILES Code: O=C(O)C(NC=O)CC1=CC=C(N(CCCl)CCCl)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 333.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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7: CHI HC, WANG CK, HAN J. [THE EFFECT OF N-FORMYL-SARCOLYSIN UPON P32 INCORPORATION INTO NUCLEIC ACIDS OF NORMAL TISSUES AND TRANSPLANTABLE TUMORS.]. Sheng Li Xue Bao. 1963 Sep;26:264-70. Chinese. PubMed PMID: 14089287.

8: HAN J, WANG CK, CHI HC, LI KT, LIU KT, CHANG HY, HO S, FAN LL, LEI HP. [STUDIES ON ANTITUMOR DRUGS. VIII. THE ANTITUMOR EFFECT OF THE ETHYL ESTER OF N-FORMYL-SARCOLYSIN- PHENYLALANINE ON EXPERIMENTAL TUMORS.]. Yao Xue Xue Bao. 1963 Aug;10:460-5. Chinese. PubMed PMID: 14081390.

9: JUEI H, CHEN-KANG W, SHIH H, HSIU-CHUAN C, KENG-T'AO L, T'IEN-HSI C, HUEI-YAN C, LI-LI F. Effect of N-formyl-sarcolysine on experimental tumors. Chin Med J. 1962 Sep;81:574-84. PubMed PMID: 14029821.

10: JUEI H, CHEN-KANG W, SHIH H, HSIU-CHUAN C, KENG-T'AO L, T'IEN-HSI C, HUEI-YAN C, LI-LI F. Effect of N-formyl-sarcolysine on experimental tumors. Chin Med J. 1962 Sep;81:574-84. PubMed PMID: 13957970.



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