WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406132
CAS#: 22978-25-2
Description: GW9662 is a potent, irreversible and selective PPARgamma antagonist, which prevented activation of PPARgamma and inhibited growth of human mammary tumour cell lines. GW9662 may permit use of anti-ER strategies to inhibit breast cancer in ER- patients.
MedKoo Cat#: 406132
Name: GW9662
CAS#: 22978-25-2
Chemical Formula: C13H9ClN2O3
Exact Mass: 276.03017
Molecular Weight: 276.67
Elemental Analysis: C, 56.43; H, 3.28; Cl, 12.81; N, 10.13; O, 17.35
GW9662, purity > 98%, is in stock. The same day shipping out after order is received.
Synonym: GW9662; GW-9662; GW 9662
IUPAC/Chemical Name: 2-Chloro-5-nitro- N -phenylbenzamide
InChi Key: DNTSIBUQMRRYIU-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H9ClN2O3/c14-12-7-6-10(16(18)19)8-11(12)13(17)15-9-4-2-1-3-5-9/h1-8H,(H,15,17)
SMILES Code: O=C(NC1=CC=CC=C1)C2=CC([N+]([O-])=O)=CC=C2Cl
The following data is based on the product molecular weight 276.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Jaudszus A, Lorkowski S, Gruen M, Roth A, Jahreis G. Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells. Int J Inflam. 2014;2014:149628. doi: 10.1155/2014/149628. Epub 2014 Jun 25. PubMed PMID: 25054074; PubMed Central PMCID: PMC4099290.