GW9662
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406132

CAS#: 22978-25-2

Description: GW9662 is a potent, irreversible and selective PPARgamma antagonist, which prevented activation of PPARgamma and inhibited growth of human mammary tumour cell lines. GW9662 may permit use of anti-ER strategies to inhibit breast cancer in ER- patients.


Chemical Structure

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GW9662
CAS# 22978-25-2

Theoretical Analysis

MedKoo Cat#: 406132
Name: GW9662
CAS#: 22978-25-2
Chemical Formula: C13H9ClN2O3
Exact Mass: 276.03017
Molecular Weight: 276.67
Elemental Analysis: C, 56.43; H, 3.28; Cl, 12.81; N, 10.13; O, 17.35

Size Price Shipping out time Quantity
50mg USD 150 Same day
100mg USD 250 Same day
200mg USD 450 Same day
500mg USD 650 Same day
1g USD 950 Same day
2g USD 1750 Same day
5g USD 2750 Same day
10g USD 3250 2 weeks
20g USD 4250 2 weeks
Inquire bulk and customized quantity

Pricing updated 2021-02-27. Prices are subject to change without notice.

GW9662, purity > 98%, is in stock. The same day shipping out after order is received.

Synonym: GW9662; GW-9662; GW 9662

IUPAC/Chemical Name: 2-Chloro-5-nitro- N -phenylbenzamide

InChi Key: DNTSIBUQMRRYIU-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H9ClN2O3/c14-12-7-6-10(16(18)19)8-11(12)13(17)15-9-4-2-1-3-5-9/h1-8H,(H,15,17)

SMILES Code: O=C(NC1=CC=CC=C1)C2=CC([N+]([O-])=O)=CC=C2Cl

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 276.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Jaudszus A, Lorkowski S, Gruen M, Roth A, Jahreis G. Limited Applicability of   GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells. Int J Inflam. 2014;2014:149628. doi: 10.1155/2014/149628. Epub 2014 Jun 25. PubMed PMID: 25054074; PubMed Central PMCID: PMC4099290.



Additional Information