WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 465960
CAS#: 2230273-76-2
Description: Safimaltib is a mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitor that also displays antineoplastic activity.
MedKoo Cat#: 465960
Name: Safimaltib
CAS#: 2230273-76-2
Chemical Formula: C20H11F6N5O2
Exact Mass: 467.0817
Molecular Weight: 467.3314
Elemental Analysis: C, 51.40; H, 2.37; F, 24.39; N, 14.99; O, 6.85
Synonym: Safimaltib; Safimaltibum; JNJ-67856633; JNJ67856633; JNJ 67856633
IUPAC/Chemical Name: 1-(1-oxo-1,2-dihydroisoquinolin-5-yl)-5-(trifluoromethyl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1H-pyrazole-4-carboxamide
InChi Key: APWRZPQBPCAXFP-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H11F6N5O2/c21-19(22,23)15-8-10(4-6-27-15)30-18(33)13-9-29-31(16(13)20(24,25)26)14-3-1-2-12-11(14)5-7-28-17(12)32/h1-9H,(H,28,32)(H,27,30,33)
SMILES Code: O=C(C1=C(C(F)(F)F)N(C2=CC=CC3=C2C=CNC3=O)N=C1)NC4=CC(C(F)(F)F)=NC=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 467.3314 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
