WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406552
Description: Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene (AGN 190299), by rapid deesterification in animals and man. AGN 190299 (“tazarotenic acid”) binds to all three members of the retinoic acid receptor (RAR) family: RARα, RARβ, and RARγ but shows relative selectivity for RARβ, and RARγ and may modify gene expression. The clinical significance of these findings is unknown.
MedKoo Cat#: 406552
Chemical Formula: C19H17NO2S
Exact Mass: 323.098
Molecular Weight: 323.40878
Elemental Analysis: C, 70.56; H, 5.30; N, 4.33; O, 9.89; S, 9.91
AGN-190229, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Synonym: AGN 190299; AGN-190299; AGN190299; Tazarotenic acid.
IUPAC/Chemical Name: 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinic acid
InChi Key: IQIBKLWBVJPOQO-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H17NO2S/c1-19(2)9-10-23-17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22)
SMILES Code: O=C(O)C1=CN=C(C#CC2=CC(C(C)(C)CCS3)=C3C=C2)C=C1
The following data is based on the product molecular weight 323.40878 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|