W146 (trifluoroacetate salt)

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471074

CAS#: 909725-62-8 (TFA);

Description: W146 TFA salt is a sphingosine-1-phosphate (S1P1) antagonist that enhances capillary leakage and restores lymphocyte egress in vivo.


Chemical Structure

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W146 (trifluoroacetate salt)
CAS# 909725-62-8 (TFA);

Theoretical Analysis

MedKoo Cat#: 471074
Name: W146 (trifluoroacetate salt)
CAS#: 909725-62-8 (TFA);
Chemical Formula: C18H28F3N2O6P
Exact Mass:
Molecular Weight: 456.4
Elemental Analysis: C, 47.37; H, 6.18; F, 12.49; N, 6.14; O, 21.03; P, 6.79

Price and Availability

Size Price Availability Quantity
1.0mg USD 270.0 2 Weeks
5.0mg USD 795.0 2 Weeks
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Related CAS #: 909725-62-8 (TFA); 909725-61-7;  

Synonym: W-146 (trifluoroacetate salt); W 146 (trifluoroacetate salt); W-146 TFA; W 146 TFA;

IUPAC/Chemical Name: [3R-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate)

InChi Key: JDWCNCPWPLHFEX-XFULWGLBSA-N

InChi Code: InChI=1S/C16H27N2O4P.C2HF3O2/c1-2-3-4-5-7-13-8-6-9-14(12-13)18-16(19)15(17)10-11-23(20,21)22;3-2(4,5)1(6)7/h6,8-9,12,15H,2-5,7,10-11,17H2,1H3,(H,18,19)(H2,20,21,22);(H,6,7)/t15-;/m1./s1

SMILES Code: O=C(NC1=CC=CC(CCCCCC)=C1)[C@H](N)CCP(O)(O)=O.O=C(O)C(F)(F)F

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 456.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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