AZD9496
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206208

CAS#: 1639042-08-2 (free base)

Description: AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.


Price and Availability

Size Price Shipping out time Quantity
10mg USD 150 Same Day
25mg USD 250 Same Day
50mg USD 450 Same Day
100mg USD 850 Same Day
200mg USD 1450 Same Day
500mg USD 2450 Same Day
1g USD 3650 Same Day
2g USD 5950 Same Day
5g USD 12650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-03. Prices are subject to change without notice.

AZD9496, purity > 98%, is in stock. The same day shipping out after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 206208
Name: AZD9496
CAS#: 1639042-08-2 (free base)
Chemical Formula: C25H25F3N2O2
Exact Mass: 442.18681
Molecular Weight: 442.48
Elemental Analysis: C, 67.86; H, 5.70; F, 12.88; N, 6.33; O, 7.23


Related CAS #: 1639042-08-2 (free base)   1639042-28-6 (maleate)    

Synonym: AZD9496; AZD-9496; AZD 9496.

IUPAC/Chemical Name: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid

InChi Key: DFBDRVGWBHBJNR-BBNFHIFMSA-N

InChi Code: InChI=1S/C25H25F3N2O2/c1-14-10-17-16-6-4-5-7-20(16)29-23(17)24(30(14)13-25(2,3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9,11-12,14,24,29H,10,13H2,1-3H3,(H,31,32)/b9-8+/t14-,24-/m1/s1

SMILES Code: O=C(O)/C=C/C1=CC(F)=C([C@H]2N(CC(C)(F)C)[C@H](C)CC3=C2NC4=C3C=CC=C4)C(F)=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


Additional Information

 Related CAS#
CAS#1639042-08-2 ( AZD9496 free base)
CAS#1639042-28-6 ( AZD9496 maleate). 
 
 
 


References