Pyrrocaine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 415013

CAS#: 2210-77-7

Description: Pyrrocaine is an anesthetic (Local)


Chemical Structure

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Pyrrocaine
CAS# 2210-77-7

Theoretical Analysis

MedKoo Cat#: 415013
Name: Pyrrocaine
CAS#: 2210-77-7
Chemical Formula: C14H20N2O
Exact Mass: 232.16
Molecular Weight: 232.330
Elemental Analysis: C, 72.38; H, 8.68; N, 12.06; O, 6.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Pyrrocaine; EN-1010; EN1010; EN 1010; NSC52644; NSC-52644; NSC 52644

IUPAC/Chemical Name: 1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-

InChi Key: OYCGKECKIVYHTN-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H20N2O/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7H,3-4,8-10H2,1-2H3,(H,15,17)

SMILES Code: O=C(NC1=C(C)C=CC=C1C)CN2CCCC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 232.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Olech E. Pyrrocaine HCl - A Preliminary Clinical Study of Its Uses in Oral Surgery. J Am Dent Soc Anesthesiol. 1963 Oct;10(8):224-9. PMID: 19598995; PMCID: PMC2067883.

2: Zsigmond EK, Patterson RL. Double-blind evaluation of a new local anesthetic agents, pyrrocaine hydrochloride, for nerve block anesthesia. Anesth Analg. 1969 Jan-Feb;48(1):66-74. PMID: 4883831.

3: de Verneuil H, Deybach JC, Phung N, Da Silva V, Nordmann Y. Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver. Biochem Pharmacol. 1983 Mar 15;32(6):1011-8. doi: 10.1016/0006-2952(83)90619-6. PMID: 6838647.

4: de Freitas JF. A rapid spectrophotometric assay of amide type dental anaesthetic agents. Aust Dent J. 1977 Jun;22(3):182-9. doi: 10.1111/j.1834-7819.1977.tb04486.x. PMID: 270977.