WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 415013
Description: Pyrrocaine is an anesthetic (Local)
MedKoo Cat#: 415013
Chemical Formula: C14H20N2O
Exact Mass: 232.1576
Molecular Weight: 232.33
Elemental Analysis: C, 72.38; H, 8.68; N, 12.06; O, 6.89
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Pyrrocaine; EN-1010; EN1010; EN 1010; NSC52644; NSC-52644; NSC 52644
IUPAC/Chemical Name: 1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-
InChi Key: OYCGKECKIVYHTN-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H20N2O/c1-11-6-5-7-12(2)14(11)15-13(17)10-16-8-3-4-9-16/h5-7H,3-4,8-10H2,1-2H3,(H,15,17)
SMILES Code: O=C(NC1=C(C)C=CC=C1C)CN2CCCC2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 232.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Olech E. Pyrrocaine HCl - A Preliminary Clinical Study of Its Uses in Oral Surgery. J Am Dent Soc Anesthesiol. 1963 Oct;10(8):224-9. PMID: 19598995; PMCID: PMC2067883.
2: Zsigmond EK, Patterson RL. Double-blind evaluation of a new local anesthetic agents, pyrrocaine hydrochloride, for nerve block anesthesia. Anesth Analg. 1969 Jan-Feb;48(1):66-74. PMID: 4883831.
3: de Verneuil H, Deybach JC, Phung N, Da Silva V, Nordmann Y. Study of anaesthetic agents for their ability to elicit porphyrin biosynthesis in chick embryo liver. Biochem Pharmacol. 1983 Mar 15;32(6):1011-8. doi: 10.1016/0006-2952(83)90619-6. PMID: 6838647.
4: de Freitas JF. A rapid spectrophotometric assay of amide type dental anaesthetic agents. Aust Dent J. 1977 Jun;22(3):182-9. doi: 10.1111/j.1834-7819.1977.tb04486.x. PMID: 270977.