YHN-86710
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 465409

CAS#: 18286-71-0

Description: YHN-86710 is an inhibitor of soluble epoxide hydrolase (sEH; IC50s = 0.155, 0.041, and 0.044 µM for the human, rat, and mouse enzymes, respectively). It is selective for sEH over fatty acid amide hydrolase (FAAH; IC50 = 10.8 µM for the human enzyme). YHN-86710 also inhibits the production of NF-κB (IC50 = 8.80 µM) and activates nuclear factor erythroid 2-related factor 2 (Nrf2; EC50 = 35.24 µM in a transactivation assay) in Neuro2a murine neuroblastoma cells. It increases the paw withdrawal threshold in a mouse model of LPS-induced inflammatory pain when administered at a dose of 100 mg/kg. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).


Chemical Structure

img
YHN-86710
CAS# 18286-71-0

Theoretical Analysis

MedKoo Cat#: 465409
Name: YHN-86710
CAS#: 18286-71-0
Chemical Formula: C25H39NO
Exact Mass: 369.3032
Molecular Weight: 369.593
Elemental Analysis: C, 81.24; H, 10.64; N, 3.79; O, 4.33

Price and Availability

Size Price Availability Quantity
1.0mg USD 210.0 2 Weeks
5.0mg USD 400.0 2 Weeks
10.0mg USD 650.0 2 Weeks
25.0mg USD 1090.0 2 Weeks
Bulk inquiry

Synonym: YHN-86710; YHN86710; YHN 86710; N-Benzyl Linoleamide; N Benzyl Linoleamide;

IUPAC/Chemical Name: (9Z,12Z)-N-benzyloctadeca-9,12-dienamide

InChi Key: YJWLCIANOBCQGW-HZJYTTRNSA-N

InChi Code: InChI=1S/C25H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-25(27)26-23-24-20-17-16-18-21-24/h6-7,9-10,16-18,20-21H,2-5,8,11-15,19,22-23H2,1H3,(H,26,27)/b7-6-,10-9-

SMILES Code: CCCCC/C=C\C/C=C\CCCCCCCC(NCC1=CC=CC=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 30.0 81.17
DMSO 30.0 81.17
Ethanol 30.0 81.17

Preparing Stock Solutions

The following data is based on the product molecular weight 369.593 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x