WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 465409
Description: YHN-86710 is an inhibitor of soluble epoxide hydrolase (sEH; IC50s = 0.155, 0.041, and 0.044 µM for the human, rat, and mouse enzymes, respectively). It is selective for sEH over fatty acid amide hydrolase (FAAH; IC50 = 10.8 µM for the human enzyme). YHN-86710 also inhibits the production of NF-κB (IC50 = 8.80 µM) and activates nuclear factor erythroid 2-related factor 2 (Nrf2; EC50 = 35.24 µM in a transactivation assay) in Neuro2a murine neuroblastoma cells. It increases the paw withdrawal threshold in a mouse model of LPS-induced inflammatory pain when administered at a dose of 100 mg/kg. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).
MedKoo Cat#: 465409
Chemical Formula: C25H39NO
Exact Mass: 369.3032
Molecular Weight: 369.593
Elemental Analysis: C, 81.24; H, 10.64; N, 3.79; O, 4.33
Synonym: YHN-86710; YHN86710; YHN 86710; N-Benzyl Linoleamide; N Benzyl Linoleamide;
IUPAC/Chemical Name: (9Z,12Z)-N-benzyloctadeca-9,12-dienamide
InChi Key: YJWLCIANOBCQGW-HZJYTTRNSA-N
InChi Code: InChI=1S/C25H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-25(27)26-23-24-20-17-16-18-21-24/h6-7,9-10,16-18,20-21H,2-5,8,11-15,19,22-23H2,1H3,(H,26,27)/b7-6-,10-9-
SMILES Code: CCCCC/C=C\C/C=C\CCCCCCCC(NCC1=CC=CC=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 369.593 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|