Calendoflavoside
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 465406

CAS#: 55033-90-4

Description: Isorhamnetin 3-O-neohesperidoside is a flavonoid glycoside that has been found in A. salicina and has antioxidant and osteoclastogenic activities. It inhibits xanthine oxidase and scavenges superoxide radicals in a cell-free assay (IC50s = 48.75 and 30 µg/ml, respectively). Isorhamnetin 3-O-neohesperidoside promotes RANKL-induced osteoclastogenesis of mouse bone marrow-derived macrophages in a concentration-dependent manner.


Chemical Structure

img
Calendoflavoside
CAS# 55033-90-4

Theoretical Analysis

MedKoo Cat#: 465406
Name: Calendoflavoside
CAS#: 55033-90-4
Chemical Formula: C28H32O16
Exact Mass: 624.17
Molecular Weight: 624.548
Elemental Analysis: C, 53.85; H, 5.16; O, 40.99

Price and Availability

Size Price Availability Quantity
10mg USD 300 2 Weeks
50mg USD 820 2 Weeks
100mg USD 1390 2 Weeks
Bulk inquiry

Synonym: Calendoflavoside; Isorhamnetin-3-O-nehesperridin; Isorhamnetin-3-O-neohesperidine; Isorhamnetin 3-O-neohesperoside; Isorhamnetin 3-O-neohesperidoside;

IUPAC/Chemical Name: 3-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one

InChi Key: QHLKSZBFIJJREC-SPSUIZEHSA-N

InChi Code: InChI=1S/C28H32O16/c1-9-18(33)21(36)23(38)27(40-9)44-26-22(37)19(34)16(8-29)42-28(26)43-25-20(35)17-13(32)6-11(30)7-15(17)41-24(25)10-3-4-12(31)14(5-10)39-2/h3-7,9,16,18-19,21-23,26-34,36-38H,8H2,1-2H3/t9-,16+,18-,19+,21+,22-,23+,26+,27-,28-/m0/s1

SMILES Code: O=C1C(O[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(OC4=CC(O)=CC(O)=C14)C5=CC=C(O)C(OC)=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 30.0 48.03
DMSO 30.0 48.03
Ethanol 30.0 48.03

Preparing Stock Solutions

The following data is based on the product molecular weight 624.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Das P, Majumder R, Mandal M, Basak P. In-Silico approach for identification of effective and stable inhibitors for COVID-19 main protease (Mpro) from flavonoid based phytochemical constituents of Calendula officinalis. J Biomol Struct Dyn. 2020 Jul 24:1-16. doi: 10.1080/07391102.2020.1796799. Epub ahead of print. PMID: 32705952; PMCID: PMC7441784.