Proguanil free base

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414746

CAS#: 500-92-5 (free base)

Description: Proguanil free base is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.

Chemical Structure

Proguanil free base
CAS# 500-92-5 (free base)

Theoretical Analysis

MedKoo Cat#: 414746
Name: Proguanil free base
CAS#: 500-92-5 (free base)
Chemical Formula: C11H16ClN5
Exact Mass: 253.11
Molecular Weight: 253.730
Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 52.07; H, 6.36; Cl, 13.97; N, 27.60

Price and Availability

Size Price Availability Quantity
25mg USD 350 2 Weeks
50mg USD 650 2 Weeks
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Related CAS #: 500-92-5 (free base)   637-32-1 (HCl)    

Synonym: Proguanil free base; BRN2811599; BRN-2811599; BRN 2811599; Chloroguanide

IUPAC/Chemical Name: Biguanide, 1-(p-chlorophenyl)-5-isopropyl-


InChi Code: InChI=1S/C11H16ClN5/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9/h3-7H,1-2H3,(H5,13,14,15,16,17)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 253.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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