ABL303

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 465384

CAS#: unknown

Description: ABL303 is a novel potent and selective inhibitor of ABHD10 (IC50 value ~ 30 nM).

Chemical Structure

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ABL303
CAS# unknown
Instruction

Theoretical Analysis

MedKoo Cat#: 465384
Name: ABL303
CAS#: unknown
Chemical Formula: C19H26N2O5
Exact Mass: 362.18
Molecular Weight: 362.426
Elemental Analysis: C, 62.97; H, 7.23; N, 7.73; O, 22.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ABL303; ABL 303; ABL-303;

IUPAC/Chemical Name: diisopropyl 3-ethyl-4-oxo-3-(p-tolyl)-1,2-diazetidine-1,2-dicarboxylate

InChi Key: OGWFJUWIADRFCX-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H26N2O5/c1-7-19(15-10-8-14(6)9-11-15)16(22)20(17(23)25-12(2)3)21(19)18(24)26-13(4)5/h8-13H,7H2,1-6H3

SMILES Code: O=C(N1N(C(OC(C)C)=O)C(C2=CC=C(C)C=C2)(CC)C1=O)OC(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 362.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zuhl AM, Mohr JT, Bachovchin DA, Niessen S, Hsu KL, Berlin JM, Dochnahl M, López-Alberca MP, Fu GC, Cravatt BF. Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition. J Am Chem Soc. 2012 Mar 21;134(11):5068-71. doi: 10.1021/ja300799t. Epub 2012 Mar 8. PMID: 22400490; PMCID: PMC3326416.