WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 206179
Description: Seletalisib, also known as UCB-5857, is a potent and selective PI3 kinase inhibitor, which may be useful for the treatment of immune-inflammatory diseases.
MedKoo Cat#: 206179
Chemical Formula: C23H14ClF3N6O
Exact Mass: 482.08697
Molecular Weight: 482.85
Elemental Analysis: C, 57.21; H, 2.92; Cl, 7.34; F, 11.80; N, 17.41; O, 3.31
Seletalisib is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Synonym: UCB-5857; UCB 5857; UCB5857; Seletalisib.
IUPAC/Chemical Name: (R)-3-(8-chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide
InChi Key: LNLJHGXOFYUARS-OAQYLSRUSA-N
InChi Code: InChI=1S/C23H14ClF3N6O/c24-16-6-1-4-13-10-15(18(31-19(13)16)14-5-3-9-33(34)11-14)21(23(25,26)27)32-22-20-17(29-12-30-22)7-2-8-28-20/h1-12,21H,(H,29,30,32)/t21-/m1/s1
SMILES Code: FC(F)(F)[C@@H](C1=CC2=CC=CC(Cl)=C2N=C1C3=CC=C[N+]([O-])=C3)NC4=C5C(C=CC=N5)=NC=N4
The following data is based on the product molecular weight 482.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|