WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414664

CAS#: 35578-20-2

Description: Oxarbazole is an antagonist of slow-reacting substance of anaphylaxis.

Chemical Structure

CAS# 35578-20-2

Theoretical Analysis

MedKoo Cat#: 414664
Name: Oxarbazole
CAS#: 35578-20-2
Chemical Formula: C21H19NO4
Exact Mass: 349.1314
Molecular Weight: 349.39
Elemental Analysis: C, 72.19; H, 5.48; N, 4.01; O, 18.32

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Oxarbazole; Win34284; Win-34284; Win 34284

IUPAC/Chemical Name: 1H-Carbazole-3-carboxylic acid, 9-benzoyl-2,3,4,9-tetrahydro-6-methoxy-


InChi Code: InChI=1S/C21H19NO4/c1-26-15-8-10-19-17(12-15)16-11-14(21(24)25)7-9-18(16)22(19)20(23)13-5-3-2-4-6-13/h2-6,8,10,12,14H,7,9,11H2,1H3,(H,24,25)

SMILES Code: O=C(C1CCC(N(C(C2=CC=CC=C2)=O)C3=C4C=C(OC)C=C3)=C4C1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 349.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Benziger D, Dorrbecker S, Goehl T, Edelson J. Absorption and disposition of oxarbazole in man and laboratory animals. Drug Metab Dispos. 1978 Jan- Feb;6(1):8-15. PMID: 23278.

2: Edelson J, Benziger DP. Disposition of a series of tetrahydrocarbazoles. Drug Metab Rev. 1980;11(2):263-89. doi: 10.3109/03602538008994027. PMID: 7011760.

3: Mielens ZE. Evaluation of the antiasthmatic potential of oxarbazole in guinea pigs. Pharmacology. 1978;17(6):323-9. doi: 10.1159/000136873. PMID: 733892.

4: Furukawa CT. Other pharmacologic agents that may affect bronchial hyperreactivity. J Allergy Clin Immunol. 1984 May;73(5 Pt 2):693-8. doi: 10.1016/0091-6749(84)90308-7. PMID: 6143771.

5: Mielens ZE, Ferguson EW, Ferrari RA. Pharmacologic characterization of immune complex induced bronchoconstriction in guinea pigs. Agents Actions. 1981 Dec;11(6-7):673-8. doi: 10.1007/BF01978788. PMID: 6462038.

6: Mielens ZE. The effects of antiasthmatic drugs against immune complex-induced bronchoconstriction in anesthetized dogs. Pharmacology. 1979;18(6):311-8. doi: 10.1159/000137271. PMID: 115021.