ORN-0829 Free Base

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MedKoo CAT#: 414637

CAS#: 2265899-49-6 (free base)

Description: ORN-0829 Free Base is a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia.


Chemical Structure

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ORN-0829 Free Base
CAS# 2265899-49-6 (free base)

Theoretical Analysis

MedKoo Cat#: 414637
Name: ORN-0829 Free Base
CAS#: 2265899-49-6 (free base)
Chemical Formula: C23H22FN7O2
Exact Mass: 447.1819
Molecular Weight: 447.47
Elemental Analysis: C, 61.74; H, 4.96; F, 4.25; N, 21.91; O, 7.15

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 2265899-49-6 (free base); 2265899-50-9 (hydrate)  

Synonym: ORN-0829 Free Base; ORN0829 Free Base; ORN 0829 Free Base

IUPAC/Chemical Name: Methanone, ((2S)-2-((3-(5-fluoro-2-pyridinyl)-1H-pyrazol-1-yl)methyl)dihydro-2H-1,3-oxazin-3(4H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)-

InChi Key: AEZZJXJIJFSUEM-QFIPXVFZSA-N

InChi Code: InChI=1S/C23H22FN7O2/c1-16-3-6-21(31-26-8-9-27-31)18(13-16)23(32)30-10-2-12-33-22(30)15-29-11-7-20(28-29)19-5-4-17(24)14-25-19/h3-9,11,13-14,22H,2,10,12,15H2,1H3/t22-/m0/s1

SMILES Code: O=C(N1[C@H](CN2N=C(C3=NC=C(F)C=C3)C=C2)OCCC1)C4=CC(C)=CC=C4N5N=CC=N5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 447.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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