Org 10325

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414609

CAS#: 79660-76-7

Description: Org 10325 has been used in the treatment of heart failure and ischaemic heart disease with Organon

Chemical Structure

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Org 10325
CAS# 79660-76-7
Instruction

Theoretical Analysis

MedKoo Cat#: 414609
Name: Org 10325
CAS#: 79660-76-7
Chemical Formula: C12H14N2O3
Exact Mass: 234.10
Molecular Weight: 234.260
Elemental Analysis: C, 61.53; H, 6.02; N, 11.96; O, 20.49

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Org 10325; Org10325; Org-10325

IUPAC/Chemical Name: N-hydroxy-5,6-dimethoxy-1H-indene-2-carboximidamide

InChi Key: WJIRZFAYYAQDLS-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H14N2O3/c1-16-10-5-7-3-9(12(13)14-15)4-8(7)6-11(10)17-2/h3,5-6,15H,4H2,1-2H3,(H2,13,14)

SMILES Code: N=C(C(C1)=CC2=C1C=C(OC)C(OC)=C2)NO

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 234.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shahid M, Martorana MG, Cottney JE, Marshall RJ. Pharmacological and biochemical effects of the cardiotonic agent Org10325 in isolated cardiac and vascular tissue preparations. Br J Pharmacol. 1990 Aug;100(4):735-42. doi: 10.1111/j.1476-5381.1990.tb14084.x. PMID: 2169938; PMCID: PMC1917585.