WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 414609
CAS#: 79660-76-7
Description: Org 10325 has been used in the treatment of heart failure and ischaemic heart disease with Organon
MedKoo Cat#: 414609
Name: Org 10325
CAS#: 79660-76-7
Chemical Formula: C12H14N2O3
Exact Mass: 234.1004
Molecular Weight: 234.26
Elemental Analysis: C, 61.53; H, 6.02; N, 11.96; O, 20.49
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Org 10325; Org10325; Org-10325
IUPAC/Chemical Name: N-hydroxy-5,6-dimethoxy-1H-indene-2-carboximidamide
InChi Key: WJIRZFAYYAQDLS-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H14N2O3/c1-16-10-5-7-3-9(12(13)14-15)4-8(7)6-11(10)17-2/h3,5-6,15H,4H2,1-2H3,(H2,13,14)
SMILES Code: N=C(C(C1)=CC2=C1C=C(OC)C(OC)=C2)NO
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 234.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Shahid M, Martorana MG, Cottney JE, Marshall RJ. Pharmacological and biochemical effects of the cardiotonic agent Org10325 in isolated cardiac and vascular tissue preparations. Br J Pharmacol. 1990 Aug;100(4):735-42. doi: 10.1111/j.1476-5381.1990.tb14084.x. PMID: 2169938; PMCID: PMC1917585.
