ONO-2921

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414582

CAS#: 253306-39-7

Description: ONO-2921 is a Novel N-Type Ca Channel Blocker


Chemical Structure

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ONO-2921
CAS# 253306-39-7

Theoretical Analysis

MedKoo Cat#: 414582
Name: ONO-2921
CAS#: 253306-39-7
Chemical Formula: C31H48N4O4S2
Exact Mass: 604.3117
Molecular Weight: 604.87
Elemental Analysis: C, 61.56; H, 8.00; N, 9.26; O, 10.58; S, 10.60

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ONO-2921; ONO2921; ONO 2921

IUPAC/Chemical Name: 3-Thiazolidinecarboxylic acid, 4-((((1R)-1-(((cyclohexylmethyl)thio)methyl)-2-oxo-2-((1-(phenylmethyl)-4-piperidinyl)amino)ethyl)amino)carbonyl)-, 1,1-dimethylethyl ester, (4R)-

InChi Key: KCVLHOGZZRHCEW-SVBPBHIXSA-N

InChi Code: InChI=1S/C31H48N4O4S2/c1-31(2,3)39-30(38)35-22-41-21-27(35)29(37)33-26(20-40-19-24-12-8-5-9-13-24)28(36)32-25-14-16-34(17-15-25)18-23-10-6-4-7-11-23/h4,6-7,10-11,24-27H,5,8-9,12-22H2,1-3H3,(H,32,36)(H,33,37)/t26-,27-/m0/s1

SMILES Code: O=C(N1CSC[C@H]1C(N[C@@H](CSCC2CCCCC2)C(NC3CCN(CC4=CC=CC=C4)CC3)=O)=O)OC(C)(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 604.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Miyazaki Y, Sugihara H, Nishiura A, Kadota K, Tozuka Y, Takeuchi H. Appropriate selection of an aggregation inhibitor of fine particles used for inhalation prepared by emulsion solvent diffusion. Drug Dev Ind Pharm. 2017 Jan;43(1):30-41. doi: 10.1080/03639045.2016.1201099. Epub 2016 Jul 12. PMID: 27297256.

2: Ozeki T, Kano Y, Takahashi N, Tagami T, Okada H. Improved bioavailability of a water-insoluble drug by inhalation of drug-containing maltosyl-β-cyclodextrin microspheres using a four-fluid nozzle spray drier. AAPS PharmSciTech. 2012 Dec;13(4):1130-7. doi: 10.1208/s12249-012-9826-z. Epub 2012 Sep 1. PMID: 22945234; PMCID: PMC3513433.