WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 465214
Description: XF048-133 is a Probe of WIN site inhibitor and PROTAC of WDR5.
MedKoo Cat#: 465214
Chemical Formula: C63H82F3N11O7S
Exact Mass: 1193.6071
Molecular Weight: 1194.4742
Elemental Analysis: C, 63.35; H, 6.92; F, 4.77; N, 12.90; O, 9.38; S, 2.68
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: XF048-133; XF048133; XF048 133;
IUPAC/Chemical Name: N1-(1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-N10-(2-(4-((4'-(4-methylpiperazin-1-yl)-3'-(6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamido)-[1,1'-biphenyl]-3-yl)methyl)piperazin-1-yl)ethyl)decanediamide
InChi Key: WJMJKBZBSNKBEY-ICEDELLMSA-N
InChi Code: InChI=1S/C63H82F3N11O7S/c1-42-57(85-41-70-42)45-19-17-43(18-20-45)37-69-60(83)53-35-48(78)40-77(53)61(84)58(62(2,3)4)72-55(80)16-11-9-7-6-8-10-15-54(79)67-23-24-74-27-29-75(30-28-74)39-44-13-12-14-46(33-44)47-21-22-52(76-31-25-73(5)26-32-76)51(34-47)71-59(82)49-38-68-56(81)36-50(49)63(64,65)66/h12-14,17-22,33-34,36,38,41,48,53,58,78H,6-11,15-16,23-32,35,37,39-40H2,1-5H3,(H,67,79)(H,68,81)(H,69,83)(H,71,82)(H,72,80)/t48-,53+,58?/m1/s1
SMILES Code: CN1CCN(C2=CC=C(C3=CC(CN4CCN(CCNC(CCCCCCCCC(NC(C(N5C[C@H](O)C[C@H]5C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)C(C)(C)C)=O)=O)CC4)=CC=C3)C=C2NC(C8=CNC(C=C8C(F)(F)F)=O)=O)CC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 1194.4742 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|