WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 414572
CAS#: 154082-13-0
Description: Omocianine is a non-specific, cyanine-based, fluorescent dye which is administered through intravenous (IV) injection.
MedKoo Cat#: 414572
Name: Omocianine
CAS#: 154082-13-0
Chemical Formula: C96H111N6O36S123-
Exact Mass: 2307.3704
Molecular Weight: 2309.67
Elemental Analysis: C, 49.92; H, 4.84; N, 3.64; O, 24.94; S, 16.66
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Omocianine; ZK203468; ZK-203468; ZK 203468
IUPAC/Chemical Name: Trihydrogen 2-((1E,3E,5E)-7-((2E)-3,3-dimethyl-5-sulfonato-1-(2-sulfonatoethyl)-1,3-dihydro-2H-indol-2-ylidene)-4-methylhepta-1,3,5-trienyl)-3,3-dimethyl-1-(2-sulfonatoethyl)-3H-indolium-5-sulfonate
InChi Key: PEHCOZUAYATSAW-UHFFFAOYSA-K
InChi Code: InChI=1S/3C32H38N2O12S4/c3*1-22(8-6-10-29-31(2,3)25-20-23(49(41,42)43)12-14-27(25)33(29)16-18-47(35,36)37)9-7-11-30-32(4,5)26-21-24(50(44,45)46)13-15-28(26)34(30)17-19-48(38,39)40/h3*6-15,20-21H,16-19H2,1-5H3,(H3-,35,36,37,38,39,40,41,42,43,44,45,46)/p-3
SMILES Code: O=S(C1=CC2=C([N+](CCS(=O)([O-])=O)=C(/C=C/C=C(C)/C=C/C=C3N(CCS(=O)([O-])=O)C4=C(C=C(S(=O)([O-])=O)C=C4)C/3(C)C)C2(C)C)C=C1)(O)=O.O=S(C5=CC6=C([N+](CCS(=O)([O-])=O)=C(/C=C/C=C(C)/C=C/C=C7N(CCS(=O)([O-])=O)C8=C(C=C(S(=O)([O-])=O)C=C8)C/7(C)C)C6(C)C)C=C5)(O)=O.O=S(C9=CC%10=C([N+](CCS(=O)([O-])=O)=C(/C=C/C=C(C)/C=C/C=C%11N(CCS(=O)([O-])=O)C%12=C(C=C(S(=O)([O-])=O)C=C%12)C/%11(C)C)C%10(C)C)C=C9)(O)=O.[H+].[H+].[H+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 2309.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Poellinger A, Persigehl T, Mahler M, Bahner M, Ponder SL, Diekmann F, Bremer C, Moesta T. Near-infrared imaging of the breast using omocianine as a fluorescent dye: results of a placebo-controlled, clinical, multicenter trial. Invest Radiol. 2011 Nov;46(11):697-704. doi: 10.1097/RLI.0b013e318229ff25. PMID: 21788905.
2: Grosenick D, Bremer C. Fluorescence Imaging of Breast Tumors and Gastrointestinal Cancer. Recent Results Cancer Res. 2020;216:591-624. doi: 10.1007/978-3-030-42618-7_18. PMID: 32594400.
3: Poellinger A. Near-infrared imaging of breast cancer using optical contrast agents. J Biophotonics. 2012 Nov;5(11-12):815-26. doi: 10.1002/jbio.201200123. PMID: 23132668.
4: van de Ven S, Wiethoff A, Nielsen T, Brendel B, van der Voort M, Nachabe R, Van der Mark M, Van Beek M, Bakker L, Fels L, Elias S, Luijten P, Mali W. A novel fluorescent imaging agent for diffuse optical tomography of the breast: first clinical experience in patients. Mol Imaging Biol. 2010 Jun;12(3):343-8. doi: 10.1007/s11307-009-0269-1. Epub 2009 Oct 2. PMID: 19798535; PMCID: PMC2864903.
