WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 414553
Description: Ofornine has vasodilator and antihypertensive activities.
MedKoo Cat#: 414553
Chemical Formula: C17H19N3O
Exact Mass: 281.1528
Molecular Weight: 281.36
Elemental Analysis: C, 72.57; H, 6.81; N, 14.94; O, 5.69
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Ofornine; Win48,049; Win-48,049; Win 48,049
IUPAC/Chemical Name: Piperidine, 1-(2-(4-pyridinylamino)benzoyl)-
InChi Key: YMODINPJYNHPTM-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H19N3O/c21-17(20-12-4-1-5-13-20)15-6-2-3-7-16(15)19-14-8-10-18-11-9-14/h2-3,6-11H,1,4-5,12-13H2,(H,18,19)
SMILES Code: O=C(N1CCCCC1)C2=CC=CC=C2NC3=CC=NC=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 281.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Aga MA, Rayees S, Rouf A, Kumar B, Sharma A, Nagaraju PVVS, Singh G, Taneja SC. Synthesis of Ofornine mimics from natural product l-vasicine as anti- hypertensive agents. Bioorg Med Chem. 2017 Feb 15;25(4):1440-1447. doi: 10.1016/j.bmc.2017.01.006. Epub 2017 Jan 6. PMID: 28110819.