TPT-172 HCl (R33)
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 504211

CAS#: 32415-42-2 (HCl)

Description: TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TPT-197; TPT-260; TPT-172.

Chemical Structure

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TPT-172 HCl (R33)
CAS# 32415-42-2 (HCl)
Handing Instruction

Theoretical Analysis

MedKoo Cat#: 504211
Name: TPT-172 HCl (R33)
CAS#: 32415-42-2 (HCl)
Chemical Formula: C6H9ClN2S2
Exact Mass: 207.9896
Molecular Weight: 208.7321
Elemental Analysis: C, 34.52; H, 4.35; Cl, 16.98; N, 13.42; S, 30.72

Size Price Shipping out time Quantity
5mg USD 120 Same Day
10mg USD 150 Same Day
25mg USD 250 Same Day
50mg USD 450 Same Day
100mg USD 650 Same Day
200mg USD 950 Same Day
500mg USD 1950 Same Day
1g USD 3450 Same Day
2g USD 5250 Same Day
Inquire bulk and customized quantity
Pricing updated 2021-02-26. Prices are subject to change without notice.

TPT-172·HCl, purity >98%, is in stock. The same day shipping out after order is received.

Related CAS #: 109841-87-4 (free base)   32415-42-2 (HCl)    

Synonym: TPT172; TPT-172; TPT 172; thiophene thiourea derivative. R33

IUPAC/Chemical Name: thiophen-2-ylmethyl carbamimidothioate hydrochloride.

InChi Key: GFYZVDOORWWFNZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C6H8N2S2.ClH/c7-6(8)10-4-5-2-1-3-9-5;/h1-3H,4H2,(H3,7,8);1H

SMILES Code: NC(SCC1=CC=CS1)=N.[H]Cl

Appearance:
white to off-white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO and water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in water

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO and water 100.0

Preparing Stock Solutions

The following data is based on the product molecular weight 208.7321 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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Dilution Calculator

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1: Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Pharmacological chaperones stabilize retromer to limit APP processing. Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20. PubMed PMID: 24747528.

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TPT-172 HCl (R33)

5mg / USD 120