ODZ10117

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464921

CAS#: unknown

Description: ODZ10117 is a STAT3 inhibitor.


Chemical Structure

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ODZ10117
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 464921
Name: ODZ10117
CAS#: unknown
Chemical Formula: C10H5Cl5N2O2
Exact Mass: 359.88
Molecular Weight: 362.412
Elemental Analysis: C, 33.14; H, 1.39; Cl, 48.91; N, 7.73; O, 8.83

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ODZ10117; ODZ 10117; ODZ-10117;

IUPAC/Chemical Name: 3-((2,4-dichlorophenoxy)methyl)-5-(trichloromethyl)-1,2,4-oxadiazole

InChi Key: KHJPDFJCROAIDO-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H5Cl5N2O2/c11-5-1-2-7(6(12)3-5)18-4-8-16-9(19-17-8)10(13,14)15/h1-3H,4H2

SMILES Code: ClC1=CC=C(OCC2=NOC(C(Cl)(Cl)Cl)=N2)C(Cl)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 362.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kim BH, Lee H, Park CG, Jeong AJ, Lee SH, Noh KH, Park JB, Lee CG, Paek SH, Kim H, Ye SK. STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model. Cells. 2020 Mar 15;9(3):722. doi: 10.3390/cells9030722. PMID: 32183406; PMCID: PMC7140655.

2: Kim BH, Lee H, Song Y, Park JS, Gadhe CG, Choi J, Lee CG, Pae AN, Kim S, Ye SK. Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy. J Clin Med. 2019 Nov 2;8(11):1847. doi: 10.3390/jcm8111847. PMID: 31684051; PMCID: PMC6912340.