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MedKoo CAT#: 202710

CAS#: 627908-92-3 (free base)

Description: SU14813 is an oral, multitargeted tyrosine kinase inhibitor (TKI) targeting vascular endothelial growth factor receptors (VEGFR), platelet-derived growth factor receptors (PDGFR), KIT, and fms-like tyrosine kinase 3 (FLT-3) (1). SU14813 was developed as a next-generation TKI agent following sunitinib (SU11248) designed to demonstrate optimized pharmacokinetic (PK) and tolerability profiles. SU14813 demonstrated broad and potent antitumor activity equivalent to that of sunitinib, which resulted in tumor regression, growth arrest, growth delay, and prolonged survival in established xenograft cancer models in mice.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 90 Same day
25mg USD 150 Same day
50mg USD 250 Same day
100mg USD 450 Same day
200mg USD 650 Same day
500mg USD 1250 Same day
1g USD 2250 Same day
2g USD 3950 Same day
5g USD 6950 Same day
Inquire bulk and customized quantity

Pricing updated 2020-09-23. Prices are subject to change without notice.

SU14813, purity > 98%, is in stock. The same day shipping out after order is received. Note: the estimated shipping out time for order > 3g may be 2 weeks.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 202710
Name: SU14813
CAS#: 627908-92-3 (free base)
Chemical Formula: C23H27FN4O4
Exact Mass: 442.20163
Molecular Weight: 442.48
Elemental Analysis: C, 62.43; H, 6.15; F, 4.29; N, 12.66; O, 14.46

Related CAS #: 452105-23-6 (Z isomer)   627908-92-3 (free base)   849643-15-8 (maleate)    

Synonym: SU14813; SU 14813; SU-14813; SU014813; SU-014813; SU 014813

IUPAC/Chemical Name: (S,Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide


InChi Code: InChI=1S/C23H27FN4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30)/b18-10-/t16-/m0/s1


Technical Data

white solid powder

>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Related CAS#
452105-23-6 ( SU14813 double Z isomer)
627908-92-3 (SU1481free base);
849643-15-8 (SU1481 maleate)