WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 464861
Description: YCH-337 is a dual tubulin−topo II inhibitor.
MedKoo Cat#: 464861
Chemical Formula: C19H14N2O3
Exact Mass: 318.1004
Molecular Weight: 318.332
Elemental Analysis: C, 71.69; H, 4.43; N, 8.80; O, 15.08
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: YCH-337; YCH337; YCH 337;
IUPAC/Chemical Name: (2-hydroxy-5-methoxyphenyl)(9H-pyrido[2,3-b]indol-3-yl)methanone
InChi Key: VXJGEBHBMOMZDB-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H14N2O3/c1-24-12-6-7-17(22)15(9-12)18(23)11-8-14-13-4-2-3-5-16(13)21-19(14)20-10-11/h2-10,22H,1H3,(H,20,21)
SMILES Code: O=C(C1=CC(OC)=CC=C1O)C2=CC3=C(N=C2)NC4=CC=CC=C43
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 318.332 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Yi JM, Zhang XF, Huan XJ, Song SS, Wang W, Tian QT, Sun YM, Chen Y, Ding J, Wang YQ, Yang CH, Miao ZH. Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition. Oncotarget. 2015 Apr 20;6(11):8960-73. doi: 10.18632/oncotarget.3264. PMID: 25840421; PMCID: PMC4496195.