Zindotrine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576994

CAS#: 56383-05-2

Description: Zindotrine is a bronchodilator.


Chemical Structure

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Zindotrine
CAS# 56383-05-2

Theoretical Analysis

MedKoo Cat#: 576994
Name: Zindotrine
CAS#: 56383-05-2
Chemical Formula: C11H15N5
Exact Mass: 217.1327
Molecular Weight: 217.28
Elemental Analysis: C, 60.81; H, 6.96; N, 32.23

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: MDL 257; MDL257; MDL-257; Zindotrine

IUPAC/Chemical Name: 1,2,4-Triazolo(4,3-b)pyridazine, 8-methyl-6-(1-piperidinyl)-

InChi Key: YYHWOTFWBVRTQD-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H15N5/c1-9-7-10(15-5-3-2-4-6-15)14-16-8-12-13-11(9)16/h7-8H,2-6H2,1H3

SMILES Code: Cc1cc(nn2cnnc12)N3CCCCC3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 217.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Kradjan WA, Hudson LD, Harris DM, Emmick GA, Pierson DJ. Single-dose efficacy and safety of zindotrine, a new oral bronchodilator. Drug Intell Clin Pharm. 1988 Oct;22(10):760-3. doi: 10.1177/106002808802201003. PMID: 3229340.

2. Küng M, Bangs SE, Gordon EE, Barker KB, Diamond L. The effect of oral zindotrine (MDL-257), a bronchial smooth muscle relaxant, on histamine airways responsiveness in asymptomatic asthmatics. Ann Allergy. 1987 Sep;59(3):201-6. PMID: 3307547.