Malvidin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576850

CAS#: 10463-84-0

Description: Malvidin is an anti-inflammatory and antioxidant that has been shown to prevent inflammatory reactions caused by lipopolysaccharide (LPS) in peripheral blood mononuclear cells (PBMCs).

Chemical Structure

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Malvidin
CAS# 10463-84-0
Instruction

Theoretical Analysis

MedKoo Cat#: 576850
Name: Malvidin
CAS#: 10463-84-0
Chemical Formula: C17H15O7
Exact Mass: 331.08
Molecular Weight: 331.300
Elemental Analysis: C, 61.63; H, 4.56; O, 33.80

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Malvidin

IUPAC/Chemical Name: Benzopyrylium, 3 5,7-trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-

InChi Key: KZMACGJDUUWFCH-UHFFFAOYSA-O

InChi Code: InChI=1S/C17H14O7/c1-22-14-3-8(4-15(23-2)16(14)21)17-12(20)7-10-11(19)5-9(18)6-13(10)24-17/h3-7H,1-2H3,(H3-,18,19,20,21)/p+1

SMILES Code: COc1cc(cc(OC)c1O)c2[o+]c3cc(O)cc(O)c3cc2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 331.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Bastin AR, Sadeghi A, Abolhassani M, Doustimotlagh AH, Mohammadi A. Malvidin prevents lipopolysaccharide-induced oxidative stress and inflammation in human peripheral blood mononuclear cells. IUBMB Life. 2020 Jul;72(7):1504-1514. doi: 10.1002/iub.2286. Epub 2020 Apr 8. PMID: 32268009.

2. Bastin A, Sadeghi A, Nematollahi MH, Abolhassani M, Mohammadi A, Akbari H. The effects of malvidin on oxidative stress parameters and inflammatory cytokines in LPS-induced human THP-1 cells. J Cell Physiol. 2021 Apr;236(4):2790-2799. doi: 10.1002/jcp.30049. Epub 2020 Sep 10. PMID: 32914418.

3. Ma Y, Li Y, Zhang H, Wang Y, Wu C, Huang W. Malvidin induces hepatic stellate cell apoptosis via the endoplasmic reticulum stress pathway and mitochondrial pathway. Food Sci Nutr. 2020 Aug 10;8(9):5095-5106. doi: 10.1002/fsn3.1810. PMID: 32994970; PMCID: PMC7500790.

4. Sakthivel KM, Kokilavani K, Kathirvelan C, Brindha D. Malvidin Abrogates Oxidative Stress and Inflammatory Mediators to Inhibit Solid and Ascitic Tumor Development in Mice. J Environ Pathol Toxicol Oncol. 2020;39(3):247-260. doi: 10.1615/JEnvironPatholToxicolOncol.2020034430. PMID: 32865916.

5. Dai T, Shi K, Chen G, Shen Y, Pan T. Malvidin attenuates pain and inflammation in rats with osteoarthritis by suppressing NF-κB signaling pathway. Inflamm Res. 2017 Dec;66(12):1075-1084. doi: 10.1007/s00011-017-1087-6. Epub 2017 Aug 29. PMID: 28852776.

6. Seo HR, Choi MJ, Choi JM, Ko JC, Ko JY, Cho EJ. Malvidin Protects WI-38 Human Fibroblast Cells Against Stress-induced Premature Senescence. J Cancer Prev. 2016 Mar;21(1):32-40. doi: 10.15430/JCP.2016.21.1.32. Epub 2016 Mar 30. PMID: 27051647; PMCID: PMC4819664.