Maltose monohydrate
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MedKoo CAT#: 576846

CAS#: 6363-53-7

Description: Maltose monohydrate is a biochemical sugar.

Chemical Structure

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Maltose monohydrate
CAS# 6363-53-7
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 576846
Name: Maltose monohydrate
CAS#: 6363-53-7
Chemical Formula: C12H24O12
Exact Mass: 360.13
Molecular Weight: 360.312
Elemental Analysis: C, 40.00; H, 6.71; O, 53.28

Price and Availability

Size Price Availability Quantity
25g USD 250 2 Weeks
100g USD 450 2 Weeks
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Synonym: beta-Maltose monohydrate; D-(+)-Maltose monohydrate; Maltose monohydrate

IUPAC/Chemical Name: beta-Maltose monohydrate

InChi Key: HBDJFVFTHLOSDW-DNDLZOGFSA-N

InChi Code: InChI=1S/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12;/h1,4-12,14-21H,2-3H2;1H2/t4-,5+,6+,7+,8+,9-,10+,11+,12+;/m0./s1

SMILES Code: O.OC[C@@H](O)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: Maltose monohydrate is a biochemical sugar.
In vitro activity: Maltose significantly improved the biomass and plantaricin EF production, which increased by 3.35 and 3.99 times comparing to the control without maltose, respectively. The maximum production of plantaricin E and F in fed-batch fermentation were 10.55 mg/L and 22.94 mg/L, respectively. Besides, qPCR results showed that maltose remarkably improved transcription of plnA, plnB, plnD, plnE, plnF, plnG1 and plnH, and heighten transcription of lamR, lamK, hpk6 and rrp6. Reference: Appl Microbiol Biotechnol. 2021 Apr;105(7):2713-2723. https://pubmed.ncbi.nlm.nih.gov/33710357/
In vivo activity: Lev-resistant (Lev-R) V. alginolyticus exhibits slow growth, reduced pathogenicity and greater resistance to killing by the host, Danio rerio (zebrafish), than Lev-sensitive (Lev-S) V. alginolyticus, suggesting that Lev-R V. alginolyticus triggers a weaker innate immune response in D. rerio than Lev-S V. alginolyticus. Maltose, a crucial metabolite, is significantly downregulated in D. rerio infected with Lev-R V. alginolyticus, and exogenous maltose enhances the immune response of D. rerio to Lev-R V. alginolyticus, leading to better clearance of the infection. Reference: Microb Biotechnol. 2020 Jul;13(4):1213-1227. https://pubmed.ncbi.nlm.nih.gov/32364684/

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMF 15.0 41.63
DMSO 15.0 41.63
PBS (pH 7.2) 10.0 27.75
Water 100.0 277.54

Preparing Stock Solutions

The following data is based on the product molecular weight 360.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: 1. Zhao D, Meng F, Zhou L, Lu F, Bie X, Sun J, Lu Z, Lu Y. Maltose effective improving production and regulatory biosynthesis of plantaricin EF in Lactobacillus plantarum 163. Appl Microbiol Biotechnol. 2021 Apr;105(7):2713-2723. doi: 10.1007/s00253-021-11218-w. Epub 2021 Mar 12. PMID: 33710357. 2. Zhang QQ, Liu ZH, Liu LL, Hu G, Lei GL, Wang Y, Cao Y, Wu W, Zhang L, Liao QP. Prebiotic Maltose Gel Can Promote the Vaginal Microbiota From BV-Related Bacteria Dominant to Lactobacillus in Rhesus Macaque. Front Microbiol. 2020 Nov 6;11:594065. doi: 10.3389/fmicb.2020.594065. PMID: 33240248; PMCID: PMC7677408. 3. Jiang M, Yang L, Chen ZG, Lai SS, Zheng J, Peng B. Exogenous maltose enhances Zebrafish immunity to levofloxacin-resistant Vibrio alginolyticus. Microb Biotechnol. 2020 Jul;13(4):1213-1227. doi: 10.1111/1751-7915.13582. Epub 2020 May 4. PMID: 32364684; PMCID: PMC7264874. 4. Ni W, Zhang Q, Liu G, Wang F, Yuan H, Guo Y, Zhang X, Xie F, Li Q, Tai G. Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro. Int Immunopharmacol. 2014 Jul;21(1):171-80. doi: 10.1016/j.intimp.2014.04.025. Epub 2014 May 10. PMID: 24825603.
In vitro protocol: 1. Zhao D, Meng F, Zhou L, Lu F, Bie X, Sun J, Lu Z, Lu Y. Maltose effective improving production and regulatory biosynthesis of plantaricin EF in Lactobacillus plantarum 163. Appl Microbiol Biotechnol. 2021 Apr;105(7):2713-2723. doi: 10.1007/s00253-021-11218-w. Epub 2021 Mar 12. PMID: 33710357. 2. Zhang QQ, Liu ZH, Liu LL, Hu G, Lei GL, Wang Y, Cao Y, Wu W, Zhang L, Liao QP. Prebiotic Maltose Gel Can Promote the Vaginal Microbiota From BV-Related Bacteria Dominant to Lactobacillus in Rhesus Macaque. Front Microbiol. 2020 Nov 6;11:594065. doi: 10.3389/fmicb.2020.594065. PMID: 33240248; PMCID: PMC7677408.
In vivo protocol: 1. Jiang M, Yang L, Chen ZG, Lai SS, Zheng J, Peng B. Exogenous maltose enhances Zebrafish immunity to levofloxacin-resistant Vibrio alginolyticus. Microb Biotechnol. 2020 Jul;13(4):1213-1227. doi: 10.1111/1751-7915.13582. Epub 2020 May 4. PMID: 32364684; PMCID: PMC7264874. 2. Ni W, Zhang Q, Liu G, Wang F, Yuan H, Guo Y, Zhang X, Xie F, Li Q, Tai G. Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro. Int Immunopharmacol. 2014 Jul;21(1):171-80. doi: 10.1016/j.intimp.2014.04.025. Epub 2014 May 10. PMID: 24825603.

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