Macluraxanthone

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559351

CAS#: 5848-14-6

Description: Macluraxanthone, a xanthone derivative, was previously reported to have many biological activities, including anti-cholinesterase, anti-oxidant, anti-cancer, anti-malarial and anti-inflammatory effects.


Chemical Structure

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Macluraxanthone
CAS# 5848-14-6

Theoretical Analysis

MedKoo Cat#: 559351
Name: Macluraxanthone
CAS#: 5848-14-6
Chemical Formula: C23H22O6
Exact Mass: 394.1416
Molecular Weight: 394.42
Elemental Analysis: C, 70.04; H, 5.62; O, 24.34

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Macluraxanthone; NSC 107228; NSC107228; NSC-107228

IUPAC/Chemical Name: 2H,6H-Pyrano(3,2-b)xanthen-6-one, 12-(1,1-dimethyl-2-propenyl)-5,9,10-trihydroxy-2,2-dimethyl-

InChi Key: XRVLGJCHUWXTDX-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H22O6/c1-6-22(2,3)15-19-12(9-10-23(4,5)29-19)17(26)14-16(25)11-7-8-13(24)18(27)20(11)28-21(14)15/h6-10,24,26-27H,1H2,2-5H3

SMILES Code: CC(C)(C=C)c1c2Oc3c(O)c(O)ccc3C(=O)c2c(O)c4C=CC(C)(C)Oc14

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 394.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Ng IMJ, Mah SH, Chua CLL. Immuno-modulatory effects of macluraxanthone on macrophage phenotype and function. Nat Prod Res. 2020 Jun 8:1-6. doi: 10.1080/14786419.2020.1775223. Epub ahead of print. PMID: 32508145.

2. Xiang Q, Wu M, Zhang L, Fu W, Yang J, Zhang B, Zheng Z, Zhang H, Lao Y, Xu H. Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury. Front Pharmacol. 2020 Apr 15;11:452. doi: 10.3389/fphar.2020.00452. PMID: 32351391; PMCID: PMC7175665.