WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559342

CAS#: 522-19-0

Description: Maculosidine is a natural furoquinoline alkaloid derived from tryptophan and anthranilic acid in plants such as Balfourodendron riedelianum. It could have cytotoxic, antimalarial, and antimicrobial activities.

Chemical Structure

CAS# 522-19-0

Theoretical Analysis

MedKoo Cat#: 559342
Name: Maculosidine
CAS#: 522-19-0
Chemical Formula: C14H13NO4
Exact Mass: 259.0845
Molecular Weight: 259.26
Elemental Analysis: C, 64.86; H, 5.05; N, 5.40; O, 24.68

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Maculosidine; Maculosidin; 4-27-00-02296; BRN 0257496; CCRIS 3578; NSC 83431; UNII-TNH45PI9WI; BRN0257496; CCRIS3578; NSC 83431; UNIITNH45PI9WI; BRN-0257496; CCRIS-3578; NSC-83431; UNII TNH45PI9WI

IUPAC/Chemical Name: Furo(2,3-b)quinoline, 4,6,8-trimethoxy-


InChi Code: InChI=1S/C14H13NO4/c1-16-8-6-10-12(11(7-8)17-2)15-14-9(4-5-19-14)13(10)18-3/h4-7H,1-3H3

SMILES Code: COc1cc(OC)c2nc3occc3c(OC)c2c1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 259.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Veiga TA, King-Díaz B, Marques AS, Sampaio OM, Vieira PC, da Silva MF, Lotina-Hennsen B. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43. doi: 10.1016/j.jphotobiol.2013.01.006. Epub 2013 Jan 23. PMID: 23416711.

2: Cui B, Chai H, Dong Y, Horgen FD, Hansen B, Madulid DA, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Quinoline alkaloids from Acronychia laurifolia. Phytochemistry. 1999 Sep;52(1):95-8. doi: 10.1016/s0031-9422(99)00039-4. PMID: 10466225.

3: El Sayed K, Al-Said MS, El-Feraly FS, Ross SA. New quinoline alkaloids from Ruta chalepensis. J Nat Prod. 2000 Jul;63(7):995-7. doi: 10.1021/np000012y. PMID: 10924184.

4: Cheplogoi PK, Mulholland DA, Coombes PH, Randrianarivelojosia M. An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae). Phytochemistry. 2008 Apr;69(6):1384-8. doi: 10.1016/j.phytochem.2007.12.013. Epub 2008 Feb 11. PMID: 18267321.