WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 559342
CAS#: 522-19-0
Description: Maculosidine is a natural furoquinoline alkaloid derived from tryptophan and anthranilic acid in plants such as Balfourodendron riedelianum. It could have cytotoxic, antimalarial, and antimicrobial activities.
MedKoo Cat#: 559342
Name: Maculosidine
CAS#: 522-19-0
Chemical Formula: C14H13NO4
Exact Mass: 259.0845
Molecular Weight: 259.26
Elemental Analysis: C, 64.86; H, 5.05; N, 5.40; O, 24.68
This product is not in stock, which may be available by custom synthesis.
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Synonym: Maculosidine; Maculosidin; 4-27-00-02296; BRN 0257496; CCRIS 3578; NSC 83431; UNII-TNH45PI9WI; BRN0257496; CCRIS3578; NSC 83431; UNIITNH45PI9WI; BRN-0257496; CCRIS-3578; NSC-83431; UNII TNH45PI9WI
IUPAC/Chemical Name: Furo(2,3-b)quinoline, 4,6,8-trimethoxy-
InChi Key: SHAVHFJCSQWTFF-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H13NO4/c1-16-8-6-10-12(11(7-8)17-2)15-14-9(4-5-19-14)13(10)18-3/h4-7H,1-3H3
SMILES Code: COc1cc(OC)c2nc3occc3c(OC)c2c1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 259.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Veiga TA, King-Díaz B, Marques AS, Sampaio OM, Vieira PC, da Silva MF, Lotina-Hennsen B. Furoquinoline alkaloids isolated from Balfourodendron riedelianum as photosynthetic inhibitors in spinach chloroplasts. J Photochem Photobiol B. 2013 Mar 5;120:36-43. doi: 10.1016/j.jphotobiol.2013.01.006. Epub 2013 Jan 23. PMID: 23416711.
2: Cui B, Chai H, Dong Y, Horgen FD, Hansen B, Madulid DA, Soejarto DD, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Quinoline alkaloids from Acronychia laurifolia. Phytochemistry. 1999 Sep;52(1):95-8. doi: 10.1016/s0031-9422(99)00039-4. PMID: 10466225.
3: El Sayed K, Al-Said MS, El-Feraly FS, Ross SA. New quinoline alkaloids from Ruta chalepensis. J Nat Prod. 2000 Jul;63(7):995-7. doi: 10.1021/np000012y. PMID: 10924184.
4: Cheplogoi PK, Mulholland DA, Coombes PH, Randrianarivelojosia M. An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae). Phytochemistry. 2008 Apr;69(6):1384-8. doi: 10.1016/j.phytochem.2007.12.013. Epub 2008 Feb 11. PMID: 18267321.
