WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 559335
Description: Mabuterol is a selective β2 adrenoreceptor agonist. Mabuterol has been found to decrease the blood pressure in rats and increase heart rate and contractile force in guinea pigs. Mabuterol inhibited the positive inotropic effect of isoprenaline but has no effect on alpha-adrenergic, acetylcholine and histamine receptors.
MedKoo Cat#: 559335
Name: Mabuterol, (R)-
Chemical Formula: C13H18ClF3N2O
Exact Mass: 310.106
Molecular Weight: 310.75
Elemental Analysis: C, 50.25; H, 5.84; Cl, 11.41; F, 18.34; N, 9.02; O, 5.15
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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Synonym: (-)-Mabuterol; (R)-(-)-Mabuterol; (R)-Mabuterol; L-Mabuterol; Mabuterol, (R)-; UNII-OLB2O2XCWH; UNIIOLB2O2XCWH; UNII OLB2O2XCWH
IUPAC/Chemical Name: Benzenemethanol, 4-amino-3-chloro-alpha-(((1,1-dimethylethyl)amino)methyl)-5-(trifluoromethyl)-, (alphaR)-
InChi Key: JSJCTEKTBOKRST-JTQLQIEISA-N
InChi Code: InChI=1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3/t10-/m0/s1
SMILES Code: CC(C)(C)NC[C@H](O)c1cc(Cl)c(N)c(c1)C(F)(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 310.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Osada E, Murai T, Ishizaka Y, Sanai K. Pharmacological studies of mabuterol, a new selective beta 2-stimulant. II: Effects on the cardiovascular system and smooth muscle organs. Arzneimittelforschung. 1984;34(11A):1641-51. PMID: 6152157.