NA 0344

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 110219

CAS#: 120925-59-9

Description: NA 0344 is a SF 2370 derivative that acts as a smooth muscle relaxant.

Chemical Structure

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NA 0344
CAS# 120925-59-9
Instruction

Theoretical Analysis

MedKoo Cat#: 110219
Name: NA 0344
CAS#: 120925-59-9
Chemical Formula: C28H26N4O3
Exact Mass: 466.20
Molecular Weight: 466.540
Elemental Analysis: C, 72.09; H, 5.62; N, 12.01; O, 10.29

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: NA 0344; NA-0344; NA0344

IUPAC/Chemical Name: 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 10-((dimethylamino)methyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-, (9S-(9alpha,10beta,12alpha))-

InChi Key: XQJTZEAYPSXVTH-XNZIZSAOSA-N

InChi Code: InChI=1S/C28H26N4O3/c1-27-28(34,14-30(2)3)12-20(35-27)31-18-10-6-4-8-15(18)22-23-17(13-29-26(23)33)21-16-9-5-7-11-19(16)32(27)25(21)24(22)31/h4-11,20,34H,12-14H2,1-3H3,(H,29,33)/t20-,27-,28+/m0/s1

SMILES Code: C[C@]12[C@@](CN(C)C)(O)C[C@@](O2)([H])N3C4=CC=CC=C4C5=C6C(CN=C6O)=C7C8=CC=CC=C8N1C7=C53

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 466.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Kohama K, Hiramura T, Takano-Ohmuro H, Ozaki H, Karaki H, Hachisu M. Effects of NA0344, a new smooth muscle relaxant, on the actin-myosin-ATP interaction and myosin light chain phosphorylation in vitro. Gen Pharmacol. 1991;22(3):465-74. doi: 10.1016/0306-3623(91)90007-s. PMID: 1869018.