Pyrromycin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559319

CAS#: 668-17-7

Description: Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.


Chemical Structure

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Pyrromycin
CAS# 668-17-7

Theoretical Analysis

MedKoo Cat#: 559319
Name: Pyrromycin
CAS#: 668-17-7
Chemical Formula: C30H35NO11
Exact Mass: 585.221
Molecular Weight: 585.61
Elemental Analysis: C, 61.53; H, 6.02; N, 2.39; O, 30.05

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Pyrromycin; Antibiotic MA144T2; MA144 T2; Antibiotic MA-144T2; MA-144 T2; Antibiotic MA 144T2; MA 144 T2; Pyromycin

IUPAC/Chemical Name: (1R-(1alpha,2beta,4beta))-2-Ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-1-naphthacenecarboxylic acid, methyl ester

InChi Key: ZJBMQVPEJHVSQA-OCYVVMCSSA-N

InChi Code: InChI=1S/C30H35NO11/c1-6-30(39)11-18(42-19-10-15(31(3)4)25(34)12(2)41-19)20-13(24(30)29(38)40-5)9-14-21(27(20)36)28(37)23-17(33)8-7-16(32)22(23)26(14)35/h7-9,12,15,18-19,24-25,32-34,36,39H,6,10-11H2,1-5H3/t12-,15-,18-,19-,24-,25+,30+/m0/s1

SMILES Code: CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O)[C@H](C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)ccc(O)c5C(=O)c4cc3[C@H]1C(=O)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 585.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Jiang, X., Dahlin, A., Weiss, S.T. et al. A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor. Sci Rep 7, 7405 (2017). https://doi.org/10.1038/s41598-017-07565-2