Obidoxime Br

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 413746

CAS#: 2337-82-8 (Br)

Description: Obidoxime Br is a member of the oxime family used to treat nerve gas poisoning.

Chemical Structure

Obidoxime Br
CAS# 2337-82-8 (Br)

Theoretical Analysis

MedKoo Cat#: 413746
Name: Obidoxime Br
CAS#: 2337-82-8 (Br)
Chemical Formula: C14H16Br2N4O3
Exact Mass:
Molecular Weight: 448.12
Elemental Analysis: C, 37.52; H, 3.60; Br, 35.66; N, 12.50; O, 10.71

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 2337-82-8 (Br)   73840-43-4 (sulfate)   4605-73-6 (iodide)   114-90-9 (Cl)  

Synonym: Obidoxime Br; S100; S-100; S 100

IUPAC/Chemical Name: Pyridinium, 1,1'-(oxydimethylene)bis(4-formyl-, dibromide, dioxime


InChi Code: InChI=1S/C14H14N4O3.2BrH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H

SMILES Code: O/N=C/C1=CC=[N+](COC[N+]2=CC=C(/C=N/O)C=C2)C=C1.[Br-].[Br-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 448.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Muckova L, Pejchal J, Jost P, Vanova N, Herman D, Jun D. Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure. Drug Chem Toxicol. 2019 May;42(3):252-256. doi: 10.1080/01480545.2018.1432641. Epub 2018 Feb 9. PMID: 29421945.

2: Inns RH, Leadbeater L. The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig. J Pharm Pharmacol. 1983 Jul;35(7):427-33. doi: 10.1111/j.2042-7158.1983.tb04316.x. PMID: 6136583.

3: Kassa J, Bajgar J. The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats. Hum Exp Toxicol. 1996 May;15(5):383-8. doi: 10.1177/096032719601500503. PMID: 8735460.

4: Hauser W, Kirsch D, Weger N. Therapeutic effects of new oximes, benactyzine and atropine in Soman poisoning: Part II. effect of HGG12, HGG42, and obidoxime in poisoning with various anticholinesterase agents in Beagle dogs. Fundam Appl Toxicol. 1981 Mar-Apr;1(2):164-8. doi: 10.1016/s0272-0590(81)80054-1. PMID: 6764202.

5: Cosar A, Kenar L. An anesthesiological approach to nerve agent victims. Mil Med. 2006 Jan;171(1):7-11. doi: 10.7205/milmed.171.1.7. PMID: 16532866.

6: Krejcová G, Kassa J. Neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in tabun-poisoned rats. Toxicology. 2003 Mar 14;185(1-2):129-39. doi: 10.1016/s0300-483x(02)00599-1. PMID: 12505451.

7: Grossmüller M, Antony J, Tränkle C, Holzgrabe U, Mohr K. Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist. Naunyn Schmiedebergs Arch Pharmacol. 2006 Jan;372(4):267-76. doi: 10.1007/s00210-005-0023-4. Epub 2005 Dec 16. PMID: 16362429.

8: Sakurada K, Ikegaya H, Ohta H, Fukushima H, Akutsu T, Watanabe K. Effects of oximes on mitochondrial oxidase activity. Toxicol Lett. 2009 Sep 10;189(2):110-4. doi: 10.1016/j.toxlet.2009.05.007. Epub 2009 May 22. PMID: 19465093.

9: Kassa J, Vachek J. A comparison of the efficacy of pyridostigmine alone and the combination of pyridostigmine with anticholinergic drugs as pharmacological pretreatment of tabun-poisoned rats and mice. Toxicology. 2002 Aug 15;177(2-3):179-85. doi: 10.1016/s0300-483x(02)00219-6. PMID: 12135621.

10: Jepsen K, Lüllmann H, Mohr K, Pfeffer J. Allosteric stabilization of 3H-N- methylscopolamine binding in guinea-pig myocardium by an antidote against organophosphate intoxication. Pharmacol Toxicol. 1988 Sep;63(3):163-8. doi: 10.1111/j.1600-0773.1988.tb00932.x. PMID: 3054859.