WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 576271
Description: Mangafodipir is a chelate of manganese that releases free manganese ions into the bloodstream after it is metabolized.
MedKoo Cat#: 576271
Chemical Formula: C22H30MnN4O14P2
Exact Mass: 691.0614
Molecular Weight: 691.38
Elemental Analysis: C, 38.22; H, 4.37; Mn, 7.95; N, 8.10; O, 32.40; P, 8.96
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
IUPAC/Chemical Name: manganese(II) (((ethane-1,2-diylbis((carboxymethyl)azanediyl))bis(methylene))bis(5-hydroxy-6-methylpyridine-4,2-diyl))bis(methylene) bis(hydrogen phosphate)
InChi Key: CXFKOLCMCRBYPL-UHFFFAOYSA-L
InChi Code: InChI=1S/C22H32N4O14P2.Mn/c1-13-21(31)15(5-17(23-13)11-39-41(33,34)35)7-25(9-19(27)28)3-4-26(10-20(29)30)8-16-6-18(12-40-42(36,37)38)24-14(2)22(16)32;/h5-6,31-32H,3-4,7-12H2,1-2H3,(H,27,28)(H,29,30)(H2,33,34,35)(H2,36,37,38);/q;+2/p-2
SMILES Code: [Mn+2].Cc1nc(COP(=O)(O)[O-])cc(CN(CCN(CC(=O)O)Cc2cc(COP(=O)(O)[O-])nc(C)c2O)CC(=O)O)c1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 691.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Qin Y, Iwase A, Murase T, Bayasula, Ishida C, Kato N, Nakamura T, Osuka S, Takikawa S, Goto M, Kotani T, Kikkawa F. Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice. Reprod Biol Endocrinol. 2018 Oct 27;16(1):106. doi: 10.1186/s12958-018-0426-y. PMID: 30368246; PMCID: PMC6204278.
2. Karlsson JOG, Andersson RG, Jynge P. Mangafodipir a Selective Cytoprotectant - with Special Reference to Oxaliplatin and Its Association to Chemotherapy-Induced Peripheral Neuropathy (CIPN). Transl Oncol. 2017 Aug;10(4):641-649. doi: 10.1016/j.tranon.2017.04.012. Epub 2017 Jun 29. PMID: 28668762; PMCID: PMC5496205.