MC-Gly-Gly-Phe
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555936

CAS#: 1599440-15-9

Description: MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).


Chemical Structure

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MC-Gly-Gly-Phe
CAS# 1599440-15-9

Theoretical Analysis

MedKoo Cat#: 555936
Name: MC-Gly-Gly-Phe
CAS#: 1599440-15-9
Chemical Formula: C23H28N4O7
Exact Mass: 472.20
Molecular Weight: 472.498
Elemental Analysis: C, 58.47; H, 5.97; N, 11.86; O, 23.70

Price and Availability

Size Price Availability Quantity
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3850 2 Weeks
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Synonym: MC-Gly-Gly-Phe;

IUPAC/Chemical Name: (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)glycylglycyl-L-phenylalanine

InChi Key: NFVPAFLSJIPUCL-KRWDZBQOSA-N

InChi Code: InChI=1S/C23H28N4O7/c28-18(9-5-2-6-12-27-21(31)10-11-22(27)32)24-14-19(29)25-15-20(30)26-17(23(33)34)13-16-7-3-1-4-8-16/h1,3-4,7-8,10-11,17H,2,5-6,9,12-15H2,(H,24,28)(H,25,29)(H,26,30)(H,33,34)/t17-/m0/s1

SMILES Code: O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Biological target: MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50.0 105.82

Preparing Stock Solutions

The following data is based on the product molecular weight 472.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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