Boc-Dap-NE
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555934

CAS#: 160800-65-7

Description: Boc-Dap-NE is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).


Chemical Structure

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Boc-Dap-NE
CAS# 160800-65-7

Theoretical Analysis

MedKoo Cat#: 555934
Name: Boc-Dap-NE
CAS#: 160800-65-7
Chemical Formula: C23H36N2O5
Exact Mass: 420.2624
Molecular Weight: 420.55
Elemental Analysis: C, 65.69; H, 8.63; N, 6.66; O, 19.02

Price and Availability

Size Price Availability Quantity
100.0mg USD 650.0 2 Weeks
200.0mg USD 1050.0 2 Weeks
500.0mg USD 1950.0 2 Weeks
1.0g USD 2950.0 2 Weeks
2.0g USD 4850.0 2 Weeks
5.0g USD 7950.0 2 Weeks
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Synonym: Boc-Dap-NE;

IUPAC/Chemical Name: tert-butyl (S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

InChi Key: XJDVGABQIFOWFC-SCQOQHIRSA-N

InChi Code: InChI=1S/C23H36N2O5/c1-15(21(27)24-16(2)19(26)17-11-8-7-9-12-17)20(29-6)18-13-10-14-25(18)22(28)30-23(3,4)5/h7-9,11-12,15-16,18-20,26H,10,13-14H2,1-6H3,(H,24,27)/t15-,16-,18+,19-,20-/m1/s1

SMILES Code: O=C(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)OC(C)(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 420.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Boc-Dap-NE

100.0mg / USD 650.0