WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406581
CAS#: 894187-61-2
Description: STF-118804 is a potent and highly specific NAMPT inhibitor ( nicotinamide phosphoribosyl transferase inhibitor), which improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells.
MedKoo Cat#: 406581
Name: STF-118804
CAS#: 894187-61-2
Chemical Formula: C25H23N3O4S
Exact Mass: 461.14093
Molecular Weight: 461.53
Elemental Analysis: C, 65.06; H, 5.02; N, 9.10; O, 13.87; S, 6.95
STF-118804, purity > 98%, is in stock. The same day shipping out after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Synonym: STF118804; STF 118804; STF118804.
IUPAC/Chemical Name: 4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
InChi Key: DLFCEZOMHBPDGI-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
SMILES Code: O=C(NCC1=CC=CN=C1)C2=CC=C(C3=NC(CS(=O)(C4=CC=C(C)C=C4)=O)=C(C)O3)C=C2
The following data is based on the product molecular weight 461.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Mei SC, Brenner C. NAD as a genotype-specific drug target. Chem Biol. 2013 Nov 21;20(11):1307-8. doi: 10.1016/j.chembiol.2013.11.001. PubMed PMID: 24267273; PubMed Central PMCID: PMC3907267.