Cyclobutyrol sodium salt

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576223

CAS#: 1130-23-0

Description: Cyclobutyrol sodium salt is a choleretic agent which also inhibits biliary lipid secretion.


Chemical Structure

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Cyclobutyrol sodium salt
CAS# 1130-23-0

Theoretical Analysis

MedKoo Cat#: 576223
Name: Cyclobutyrol sodium salt
CAS#: 1130-23-0
Chemical Formula: C10H17NaO3
Exact Mass: 208.11
Molecular Weight: 208.230
Elemental Analysis: C, 57.68; H, 8.23; Na, 11.04; O, 23.05

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Cyclobutyrol natrium; Cyclobutyrol sodium salt; Epa-Bon; Hebucol; Tri-Bil

IUPAC/Chemical Name: sodium 2-(1-hydroxycyclohexyl)butanoate

InChi Key: ZIKJCAPMXXTMDD-UHFFFAOYSA-M

InChi Code: InChI=1S/C10H18O3.Na/c1-2-8(9(11)12)10(13)6-4-3-5-7-10;/h8,13H,2-7H2,1H3,(H,11,12);/q;+1/p-1

SMILES Code: [Na+].CCC(C(=O)[O-])C1(O)CCCCC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 208.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Monte MJ, Parslow RA, Coleman R. Inhibitory action of cyclobutyrol on the secretion of biliary cholesterol and phospholipids. Biochem J. 1990 Feb 15;266(1):165-71. PubMed PMID: 2310370; PubMed Central PMCID: PMC1131110.

2: Monte MJ, Aybar R, Cava F, Esteller A, Jimenez R. Choleretic mechanism and effects of cyclobutyrol in the rat: dose-response relationship. Biomed Biochim Acta. 1990;49(1):83-90. PubMed PMID: 2360911.

3: Monte MJ, Cava F, Esteller A, Jimenez R. Inhibition of biliary cholesterol and phospholipid secretion during cyclobutyrol-induced hydrocholeresis. Biochem J. 1989 Oct 15;263(2):513-8. PubMed PMID: 2574569; PubMed Central PMCID: PMC1133458.

4: BLANC B, BLANC-CUTTOLI P. [A NEW MEDICATION FOR DIGESTIVE DISORDERS OF HEPATO-BILIARY ORIGIN: COMBINATION OF SODIUM CYCLOBUTYROL, SORBITOL AND ATROPINE SULFATE]. J Med Lyon. 1964 Oct 5;45:1679-89. French. PubMed PMID: 14205635.

5: NISHIMURA M, NAKAMATA T, SATO J, NAKAYAMA K. [On the bile-flow increasing action of the new cholagogue Lipotrin. Study of clinical trial results]. Chiryo. 1963 Aug;45:1473-80. Japanese. PubMed PMID: 13938784.