WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 463997
Description: 7,12-Diketolithocholic acid is a bile acid. Plasma levels of 7,12-diketolithocholic acid are increased in patients with cholestasis.
MedKoo Cat#: 463997
Chemical Formula: C24H36O5
Exact Mass: 404.2563
Molecular Weight: 404.547
Elemental Analysis: C, 71.26; H, 8.97; O, 19.77
Synonym: 7,12-diketo-LCA; 3-hydroxy-7,12-Diketocholanoic Acid; 7,12-Dioxolithocholic Acid; 7,12-Diketolithocholic Acid;
IUPAC/Chemical Name: (R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7,12-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChi Key: MAFJMPFLJJCSTB-FQBQTYDJSA-N
InChi Code: InChI=1S/C24H36O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,22,25H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,22+,23+,24-/m1/s1
SMILES Code: O=C1[C@]2([C@]3([C@@](C(C[C@@]2([C@]4(C)[C@]([H])(C1)C[C@H](O)CC4)[H])=O)(C)[C@]([H])(CC3)[C@H](C)CCC(O)=O)[H])[H]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 404.547 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|