WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463988

CAS#: unknown

Description: WV970 a multikinase inhibitor (IC50 in the nanomolar range) that displays anti-influenza activity. It inhibits multiple kinases, including JAK-2, with 61% inhibition at 50 nM. Its antiviral activity is similar to that of oseltamivir carboxylate (IC50 0.012 μM), which is a currently available antiviral drug. It exhibits potent antiviral activity against the influenza A strain A/Udorn/307/1972 (H3N2) and influenza B strains B/Yamagata/16/88 and B/Nagasaki/1/87

Chemical Structure

CAS# unknown

Theoretical Analysis

MedKoo Cat#: 463988
Name: WV970
CAS#: unknown
Chemical Formula: C26H29N3O2S
Exact Mass: 447.198
Molecular Weight: 447.597
Elemental Analysis: C, 69.77; H, 6.53; N, 9.39; O, 7.15; S, 7.16

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: WV970; WV 970; WV-970;

IUPAC/Chemical Name: 3-((5-cyclopropyl-4-oxo-3-((S)-1-phenylethyl)-2-thioxoimidazolidin-1-yl)methyl)-7,8-dimethyl-4a,8a-dihydroquinolin-2(1H)-one


InChi Code: InChI=1S/C26H29N3O2S/c1-15-9-10-20-13-21(24(30)27-22(20)16(15)2)14-28-23(19-11-12-19)25(31)29(26(28)32)17(3)18-7-5-4-6-8-18/h4-10,13,17,19-20,22-23H,11-12,14H2,1-3H3,(H,27,30)/t17-,20?,22?,23?/m0/s1

SMILES Code: O=C(N([C@@H](C)C1=CC=CC=C1)C2=S)C(C3CC3)N2CC4=CC(C=CC(C)=C5C)C5NC4=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 447.597 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Sasaki Y, Kakisaka M, Chutiwitoonchai N, Tajima S, Hikono H, Saito T, Aida Y. Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity. Biochem Biophys Res Commun. 2014 Jul 18;450(1):49-54. doi: 10.1016/j.bbrc.2014.05.058. Epub 2014 May 22. PMID: 24858693.