XUN01966

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555909

CAS#: 122501-96-6

Description: XUN01966 is a ligand for aldo-​keto reductases and fluorogenic probe. It was reported in WO 2006023821. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

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XUN01966
CAS# 122501-96-6
Instruction

Theoretical Analysis

MedKoo Cat#: 555909
Name: XUN01966
CAS#: 122501-96-6
Chemical Formula: C17H17NO3
Exact Mass: 283.12
Molecular Weight: 283.327
Elemental Analysis: C, 72.07; H, 6.05; N, 4.94; O, 16.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: XUN01966; XUN-01966; XUN 01966;

IUPAC/Chemical Name: 8-acetyl-2,3,5,6-tetrahydro-1h,4h-11-oxa-3a-azabenzo[de]anthracen-10-one

InChi Key: XQARIKRDYJHYTM-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H17NO3/c1-10(19)13-9-15(20)21-17-12-5-3-7-18-6-2-4-11(16(12)18)8-14(13)17/h8-9H,2-7H2,1H3

SMILES Code: O=C1OC2=C3C4=C(CCCN4CCC3)C=C2C(C(C)=O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: The photophys. properties of XUN01966 were λmax of 436 nm, ε 12,​900 ± 200 M-​1cm-​1, λem 520 nm, and Φ 0.00080 ±0.00008. The AKR1Cs kinetic data of the fluorogenic substrates were also detd. XUN01966 showed Km 24.4 ± 2.3 μM, Kcat 1.1 min-​1, and catalytic efficiency (Kcat/Km) (CE) 0.0, 46 for AKR1C1; Km 7.3 ± 0.4 μM, Kcat 14.8 min-​1, CE 2.1 for AKR1C2; Km 1.1 ± 0.1 μM, Kcat 7.5 min-​1, CE 6.9 for AKR1C3; and Km 20.6 ± 1.9 μM, Kcat 0.38 min-​1, CE 0.0, and 20 for AKR1C4. XUN01966 was found to be a selective probe for 3α-​hydroxysteroid dehydrogenases.

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 283.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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