WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 463947

CAS#: 677746-25-7

Description: K162 is a novel Inhibitor of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation.

Chemical Structure

CAS# 677746-25-7

Theoretical Analysis

MedKoo Cat#: 463947
Name: K162
CAS#: 677746-25-7
Chemical Formula: C15H14BrN
Exact Mass: 287.031
Molecular Weight: 288.188
Elemental Analysis: C, 62.52; H, 4.90; Br, 27.73; N, 4.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: K162; K 162; K-162; K01-162; K01162; K01 162;

IUPAC/Chemical Name: 7-bromo-N,N-dimethyl-9H-fluoren-2-amine


InChi Code: InChI=1S/C15H14BrN/c1-17(2)13-4-6-15-11(9-13)7-10-8-12(16)3-5-14(10)15/h3-6,8-9H,7H2,1-2H3

SMILES Code: CN(C)C1=CC(CC2=C3C=CC(Br)=C2)=C3C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 288.188 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Mrdenovic D, Zarzycki P, Majewska M, Pieta IS, Nowakowski R, Kutner W, Lipkowski J, Pieta P. Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162. ACS Chem Neurosci. 2021 Jan 22. doi: 10.1021/acschemneuro.0c00754. Epub ahead of print. PMID: 33478212.