p-Fluorophenylalanine
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MedKoo CAT#: 463931

CAS#: 51-65-0

Description: p-Fluorophenylalanine inhibits mitosis and reversibly arrests HeLa cells in G2. p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis.


Chemical Structure

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p-Fluorophenylalanine
CAS# 51-65-0

Theoretical Analysis

MedKoo Cat#: 463931
Name: p-Fluorophenylalanine
CAS#: 51-65-0
Chemical Formula: C9H10FNO2
Exact Mass: 183.0696
Molecular Weight: 183.1824
Elemental Analysis: C, 59.01; H, 5.50; F, 10.37; N, 7.65; O, 17.47

Price and Availability

Size Price Availability Quantity
1.0g USD 240.0 2 Weeks
5.0g USD 500.0 2 Weeks
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Synonym: p-Fluorophenylalanine; p Fluorophenylalanine; 4-Fluorophenylalanine; 4 Fluorophenylalanine; 4-Fluoro-dl-para-phenylalanine; NSC 71433; NSC71433; NSC-71433;

IUPAC/Chemical Name: 2-amino-3-(4-fluorophenyl)propanoic acid

InChi Key: XWHHYOYVRVGJJY-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

SMILES Code: NC(C(O)=O)Cc1ccc(F)cc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 183.1824 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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