G-4120

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575755

CAS#: 143120-27-8

Description: G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.

Chemical Structure

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G-4120
CAS# 143120-27-8
Instruction

Theoretical Analysis

MedKoo Cat#: 575755
Name: G-4120
CAS#: 143120-27-8
Chemical Formula: C26H36N8O11S
Exact Mass: 668.22
Molecular Weight: 668.680
Elemental Analysis: C, 46.70; H, 5.43; N, 16.76; O, 26.32; S, 4.79

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: G 4120; G-4120; G4120

IUPAC/Chemical Name: (3R,6S,12S,15R)-6-(carboxymethyl)-12-(3-guanidinopropyl)-15-(4-hydroxybenzyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacyclooctadecane-3-carboxylic acid 1-oxide

InChi Key: DMXRDQJVBMEHPP-OREKCURGSA-N

InChi Code: InChI=1S/C26H36N8O11S/c27-26(28)29-7-1-2-15-22(40)30-10-19(36)31-17(9-21(38)39)24(42)34-18(25(43)44)11-46(45)12-20(37)32-16(23(41)33-15)8-13-3-5-14(35)6-4-13/h3-6,15-18,35H,1-2,7-12H2,(H,30,40)(H,31,36)(H,32,37)(H,33,41)(H,34,42)(H,38,39)(H,43,44)(H4,27,28,29)/t15-,16+,17-,18-,46?/m0/s1

SMILES Code: NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CS(=O)C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC1=O)C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:
Product Data
Instruction:
View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 668.680000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Stockmans F, Stassen JM, Vermylen J, Hoylaerts MF, Nyström A. A technique to investigate microvascular mural thrombus formation in arteries and veins: II. Effects of aspirin, heparin, r-hirudin, and G-4120. Ann Plast Surg. 1997 Jan;38(1):63-8. doi: 10.1097/00000637-199701000-00012. PMID: 9015542. 2. Barker PL, Bullens S, Bunting S, Burdick DJ, Chan KS, Deisher T, Eigenbrot C, Gadek TR, Gantzos R, Lipari MT, et al. Cyclic RGD peptide analogues as antiplatelet antithrombotics. J Med Chem. 1992 May 29;35(11):2040-8. doi: 10.1021/jm00089a014. PMID: 1597855.