Cyprolidol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412929

CAS#: 4904-00-1 (free base)

Description: Cyprolidol is an antidepressant

Chemical Structure

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Cyprolidol
CAS# 4904-00-1 (free base)
Instruction

Theoretical Analysis

MedKoo Cat#: 412929
Name: Cyprolidol
CAS#: 4904-00-1 (free base)
Chemical Formula: C21H19NO
Exact Mass: 301.15
Molecular Weight: 301.390
Elemental Analysis: C, 83.69; H, 6.35; N, 4.65; O, 5.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 2364-72-9 (HCl)   4904-00-1 (free base)  

Synonym: Cyprolidol; Cyprolidolum; UNII-321552050N

IUPAC/Chemical Name: Methanol, diphenyl(2-(4-pyridyl)cyclopropyl)-, (E)-

InChi Key: KPUSUIKQQCFQCX-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H19NO/c23-21(17-7-3-1-4-8-17,18-9-5-2-6-10-18)20-15-19(20)16-11-13-22-14-12-16/h1-14,19-20,23H,15H2

SMILES Code: OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3C(C4=CC=NC=C4)C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 100.00

Preparing Stock Solutions

The following data is based on the product molecular weight 301.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hekimian LJ, Gershon S, Floyd A. Cyprolidol and imipramine: a double-blind controlled study in endogenous depression. Arzneimittelforschung. 1969 Jun;19(6):955-6. PMID: 4896165.

2: Korol B, Brown ML, Sletten IW. Effects of a new antidepressant cyprolidol (IN-1060) upon the blood pressure responses to autonomic drugs in conscious dogs. Curr Ther Res Clin Exp. 1966 Nov;8(11):543-8. PMID: 4963159.

3: Brown ML, Gershon S, Korol B. Some pharmacological effects of a new potential antidepressant cyprolidol (IN-1060) compared with imipramine. Med Pharmacol Exp Int J Exp Med. 1966;15(4):329-43. doi: 10.1159/000135886. PMID: 6012765.

4: Miller L, Napoli M, O'Dell TB. Pharmacological evaluation of a potential psychotherapeutic agent: cyprolidol, a pyridylcyclopropane derivative. Arch Int Pharmacodyn Ther. 1967 Apr;166(2):313-23. PMID: 4963240.